SynthesisObesity surgery2026
The Effects of Long-Term Exercise Intervention on Cardiovascular Health Outcomes in Patients after Metabolic and Bariatric Surgery: a Systematic Review and Meta-Analysis.
Synthesis in Obesity surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAlthough exercise training is known to benefit cardiovascular health, its specific effects on cardiovascular parameters in patients after Metabolic and bariatric surgery remain unclear. This study aimed to synthesize the latest evidence through a systematic review and meta-analysis to evaluate the effectiveness of long-term exercise interventions (≥ 12 weeks) in improving cardiovascular health outcomes in postoperative patients, thereby providing a scientific basis for clinical rehabilitation.
methodsUp to July 26, 2025, we systematically searched PubMed, Web of Science, EMBASE, Scopus, and the Cochrane Central Register of Controlled Trials for relevant randomized controlled trials (RCTs). The evaluated outcomes included body weight, body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP), high-density lipoprotein (HDL), low-density lipoprotein (LDL), heart rate (HR), fat mass, lean mass, VO₂max/peak relative to body weight, and fasting insulin.
resultsA total of 17 studies involving 855 postoperative MBS patients were included. The interventions started at different postoperative time points, ranging from immediately after surgery to 12 months post-MBS.The duration of the intervention also varies, with the shortest being 12 weeks and the longest 52 weeks. The findings indicated that long-term exercise interventions significantly improved HDL (95% CI: 2.05 to 6.43, P = 0.0001); VO₂max/peak relative to body weight (95% CI: 1.91 to 5.68, P < 0.00001), and was associated with a decrease in HR (95% CI: -11.70 to 0.04, P = 0.05, However, other metabolic indicators such as LDL, fat mass, lean mass, fasting insulin, and blood pressure did not reach statistical significance (LDL: MD = 3.60, 95% CI: -2.87 to 10.08, P = 0.28; fat mass: MD=-0.23, 95% CI: -1.75 to 1.28, P = 0.76; lean mass: MD=-0.12, 95% CI: -1.86 to 1.61, P = 0.89; fasting insulin: MD=-1.10, 95% CI: -2.30 to 0.10, P = 0.07; SBP: MD=-1.25, 95% CI: -4.01 to 1.51, P = 0.37; DBP: MD=-0.48, 95% CI: -2.39 to 1.42, P = 0.62).
conclusionLong-term exercise interventions demonstrate selective metabolic benefits in patients after bariatric surgery, with core advantages observed in enhanced cardiopulmonary function and HDL modulation. A non-significant trend toward lower insulin levels was observed, suggesting that exercise may be associated with favorable metabolic regulation; however, this finding should be interpreted cautiously and requires confirmation in adequately powered, dose–response studies with stratified intervention designs.
Indexed as
Identifiers
41896445What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.