Evidence map›Paper›PMID 41897367›Full record

ArticleBiomolecules2026

Effects of Carvacrol on Aortic Damage in a Streptozotocin-Induced Type 1 Diabetic Rat Model.

Seda Cetinkaya Karabekir, Burcu Gultekin, Hasan Basri Savas, Gokhan Cuce, Serpil Kalkan

Abstract read
In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Seda Cetinkaya KarabekirDepartment of Histology and Embryology, Faculty of Medicine, Izmir Bakırcay University, Izmir 35665, Turkey.ORCID 0000-0003-2622-7062
Burcu GultekinDepartment of Histology and Embryology, Faculty of Medicine, Necmettin Erbakan University, Meram, Konya 42090, Turkey.ORCID 0000-0001-6461-8123
Hasan Basri SavasDepartment of Medical Biochemistry, Faculty of Medicine, Mardin Artuklu University, Mardin 47000, Turkey.ORCID 0000-0001-8759-4507
Gokhan CuceDepartment of Histology and Embryology, Faculty of Medicine, Necmettin Erbakan University, Meram, Konya 42090, Turkey.ORCID 0000-0003-1781-5292
Serpil KalkanDepartment of Histology and Embryology, Faculty of Medicine, Necmettin Erbakan University, Meram, Konya 42090, Turkey.ORCID 0000-0003-0076-9154

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes mellitus (DM) is associated with vascular complications that increase morbidity and mortality. Natural antioxidants play a vital role in reducing diabetes-related damage. This study investigated the protective effects of the phenolic monoterpene carvacrol (CAR) against diabetic complications. Thirty-two male Wistar Albino rats (4 months, 250-300 g) were divided into four groups: control, DM, DM + DMSO, and DM + CAR. Type 1 diabetes was induced via intraperitoneal injection of 50 mg/kg streptozotocin (STZ). The DM + CAR group received 20 mg/kg CAR daily for four weeks. Body weight and blood glucose levels were regularly monitored. At the end of the study, aortic tissues were examined using hematoxylin-eosin (H&E), Verhoeff-Van Gieson, and immunohistochemical staining, while cardiac tissues were analyzed with H&E and Masson's trichrome. Serum levels of ischemia-modified albumin (IMA), cholesterol (CHOL), triglycerides (TG), and high-density lipoprotein (HDL) were measured. In the DM group, IMA and CHOL levels were increased (

Indexed as

AortaCymenesDiabetes Mellitus, ExperimentalDiabetes Mellitus, Type 1AnimalsAntioxidantsApoptosisBlood GlucoseCaspase 3MaleOxidative StressRatsRats, WistarStreptozocinAntioxidantsBlood GlucosecarvacrolCaspase 3CymenesStreptozocinapoptosiscarvacroldiabetes mellitusischemia-modified albuminoxidative stressSTZ-induced diabetesvascular complications

Identifiers

PMID41897367
PMCPMC13023609

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.