Evidence map›Paper›PMID 41897763›Full record

ReviewFoods (Basel, Switzerland)2026

Cascade Valorisation of Lemon Processing Residues (Part II): Integrated Biorefinery Design, Circular Economy, and Techno-Economic Feasibility.

Jimmy Núñez-Pérez, Jhomaira L Burbano-García, Rosario Espín-Valladares, Marco V Lara-Fiallos, Juan Carlos DelaVega-Quintero, Marcelo Cevallos-Vallejos, José-Manuel Pais-Chanfrau

Abstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jimmy Núñez-PérezSchool of Agro-Industrial Engineering, Facultad de Ingenieria en Ciencias Agropecuarias y Ambientales (FICAYA), Universidad Técnica del Norte, Ibarra 100105, Imbabura, Ecuador.ORCID 0000-0001-6808-4886
Jhomaira L Burbano-GarcíaSchool of Agro-Industrial Engineering, Facultad de Ingenieria en Ciencias Agropecuarias y Ambientales (FICAYA), Universidad Técnica del Norte, Ibarra 100105, Imbabura, Ecuador.ORCID 0009-0008-3552-3641
Rosario Espín-ValladaresSchool of Agro-Industrial Engineering, Facultad de Ingenieria en Ciencias Agropecuarias y Ambientales (FICAYA), Universidad Técnica del Norte, Ibarra 100105, Imbabura, Ecuador.ORCID 0000-0002-2634-1482
Marco V Lara-FiallosSchool of Agro-Industrial Engineering, Facultad de Ingenieria en Ciencias Agropecuarias y Ambientales (FICAYA), Universidad Técnica del Norte, Ibarra 100105, Imbabura, Ecuador.ORCID 0000-0003-2713-8395
Juan Carlos DelaVega-QuinteroSchool of Agro-Industrial Engineering, Facultad de Ingenieria en Ciencias Agropecuarias y Ambientales (FICAYA), Universidad Técnica del Norte, Ibarra 100105, Imbabura, Ecuador.ORCID 0000-0002-8451-7108
Marcelo Cevallos-VallejosFacultad de Ingenieria en Ciencias Agropecuarias y Ambientales (FICAYA), Universidad Técnica del Norte, Ibarra 100105, Imbabura, Ecuador.ORCID 0000-0001-8151-2785
José-Manuel Pais-ChanfrauSchool of Agro-Industrial Engineering, Facultad de Ingenieria en Ciencias Agropecuarias y Ambientales (FICAYA), Universidad Técnica del Norte, Ibarra 100105, Imbabura, Ecuador.ORCID 0000-0003-2829-543X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review examines the implementation dimensions of integrated lemon biorefinery systems, including cascade valorisation design, circular-economy integration, life-cycle assessment, techno-economic feasibility, and regulatory frameworks. Bibliometric analysis of Web of Science data (2015-2025) reveals exponential growth in citrus-biorefinery research, with lemon representing a burgeoning subset. Techno-economic assessments indicate that cascade biorefineries recovering essential oils, pectin, polyphenols, nanocellulose, and bioenergy can achieve cumulative revenues of USD 400-650 per tonne of dry peel. Whilst small-scale units (<500 tonnes per year) struggle to achieve viability, industrial simulations demonstrate Internal Rates of Return exceeding 18% at processing scales above 100,000 tonnes annually (2025 basis). Life-cycle assessments confirm environmental benefits, with greenhouse gas reductions of 60-85% relative to conventional disposal. Critical success factors include adopting green extraction technologies to preserve bioactive integrity and mitigating D-limonene inhibition in downstream anaerobic digestion. These findings establish essential oil extraction and pectin recovery as commercially mature technologies, whilst integrated multi-product lemon biorefineries remain economically promising based on techno-economic modelling and pilot-scale demonstrations, provided regulatory hurdles are effectively navigated.

Indexed as

cascade extractioncircular bioeconomycitrus waste valorisationD-limoneneindustrial symbiosislemon biorefineryLife Cycle Assessment (LCA)nanocrystalline cellulosepectin recoveryTechno Economic Analysis (TEA)

Identifiers

PMID41897763
PMCPMC13025514

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.