Evidence map›Paper›PMID 41898128›Full record

ReviewBehavioral sciences (Basel, Switzerland)2026

Know Your Nose: A Narrative Review of the Developmental and Functional Impact and Importance of the Nose, Nasal Breathing and Techniques on Health and Emotional Wellbeing.

Alireza Amirsadri, Hooman Sedighi

Abstract readReview
In one paragraph

Review in Behavioral sciences (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alireza AmirsadriDepartment of Psychiatry and Behavioral Neurosciences, School of Medicine, Wayne State University, Detroit, MI 48201, USA.ORCID 0000-0002-8075-902X
Hooman SedighiPhysical Medicine Consultants, Dallas, TX 75235, USA.ORCID 0009-0007-2224-4128

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This narrative review synthesizes research demonstrating the multi-domain import of nasal breathing across developmental, physiological, immunological, and neuropsychological domains, with the aim of communicating its potential clinical relevance and motivating future empirical investigation. We broadly address developmental and evolutionary foundations and the pathways through which nasal breathing influences health, functioning, and subjective experience. Across these areas, evidence implicates nasal breathing in immune defense, autonomic and emotion regulation, limbic entrainment, and aspects of consciousness. Notably, many contemplative traditions-including yogic pranayama, Sufi, and Buddhist practices-have long emphasized nasal breathing for its physical and spiritual benefits, and contemporary evidence increasingly buttresses components of these traditional beliefs, with growing convergence between contemporary scientific findings and longstanding traditional observation. More broadly, the epistemic basis of the evidence supporting nasal breathing's effects reviewed here ranges considerably, from well-controlled experimental and mechanistic work to preliminary and small-sample studies whose clinical translation remains tenuous, and specific therapeutic inferences should be made cautiously. Nonetheless, nasal breathing represents an underappreciated, low-cost, and accessible adjunctive approach with genuine clinical potential. Realizing that potential will require controlled trials attending to parameter specificity-e.g., respiratory phase, laterality, and rate-and designs that isolate nasal breathing from other aspects of contemplative practices across well-defined populations and outcomes.

Indexed as

autonomic nervous systemnasal breathingnitric oxidepsychological wellbeingtraditional breathing practices

Identifiers

PMID41898128
PMCPMC13023532

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.