ReviewBiomedicines2026
A Review of Gut Microbiota Dynamics: From Healthy Gestation to Gestational Diabetes in Human and Mouse Models.
Review in Biomedicines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Maternal Metformin Exposure Induces Gut Microbial Shifts in Non-Diabetic Dams and Sex-Stratified Changes in Mouse Offspring.Biomolecules · 2026Article
- Maternal Microbiome in Gestational Diabetes Mellitus: Mechanisms, Biomarkers, and Therapeutic Perspectives.Life (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the past decades, gut microbiota has emerged as a critical modulator of human health and disease. Pregnancy involves substantial microbiota remodelling that influences offspring development, yet mechanisms linking maternal microbiota changes to gestational diabetes mellitus (GDM) remain unclear. The current literature lacks a comprehensive synthesis of pregnancy microbiota dynamics across healthy gestation to GDM, comparative human-murine analysis, and pregnancy-specific mechanistic frameworks distinct from type 2 diabetes models. This narrative review comprehensively synthesised evidence on gut microbiota composition in healthy pregnancy and GDM (2005-2025, NCBI PubMed) to identify convergent signatures and articulate pregnancy-specific mechanisms. Early pregnancy microbiota resembles non-pregnant individuals, whereas late pregnancy exhibits increased lactic acid-producing bacteria and reduced Firmicutes-to-Bacteroidetes (F/B) ratios. GDM exhibits pathological dysbiosis with elevated F/B ratios and reduced
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.