Evidence map›Paper›PMID 41898705›Full record

ArticleInternational journal of molecular sciences2026

Dihydroquercetin in Obesity and Prediabetes: Case Report and Insights from Molecular Modeling.

Roman P Terekhov, Amir Taldaev, Artem A Svotin, Denis I Pankov, Evgenia M Sukhova, David A Manukov, Ketelina Bergel, Maria D Korochkina, Irina A Selivanova

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Roman P TerekhovNelyubin Institute of Pharmacy, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.ORCID 0000-0001-9206-8632
Amir TaldaevLaboratory for the Study of Single Biomacromolecules, Institute of Biomedical Chemistry, 119121 Moscow, Russia.
Artem A SvotinNelyubin Institute of Pharmacy, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.ORCID 0009-0001-5360-8816
Denis I PankovNelyubin Institute of Pharmacy, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.ORCID 0009-0007-6195-6400
Evgenia M SukhovaNelyubin Institute of Pharmacy, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.ORCID 0009-0005-7038-7081
David A ManukovNelyubin Institute of Pharmacy, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Ketelina BergelNelyubin Institute of Pharmacy, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Maria D KorochkinaNelyubin Institute of Pharmacy, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.ORCID 0000-0002-2790-9041
Irina A SelivanovaNelyubin Institute of Pharmacy, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.ORCID 0000-0002-2244-445X

Funding

Russian Science Foundation 25-75-00071
6 · The paper itself

Abstract

Dihydroquercetin (DHQ) is a promising object for the development of a treatment for patients with obesity and prediabetes requiring a moderate therapeutic effect. This paper reports a clinical case of DHQ application in a 30-year-old Caucasian male and proposes a molecular mechanism of its anti-obesity effect. DHQ was administrated as a dietary supplement at a dose of 100-200 mg/day during 3 months with treatment interruption for 1 month. The data collected one month before the treatment were used as a control. The molecular aspects were studied via molecular docking with β

Indexed as

ObesityPrediabetic StateQuercetinAdultHumansMaleMolecular Docking SimulationMolecular Dynamics SimulationPPAR gammaReceptors, Adrenergic, beta-3PPAR gammaQuercetinReceptors, Adrenergic, beta-3taxifolinclinical casedihydroquercetinflavonoidmolecular dockingmolecular dynamicsobesityprediabetes

Identifiers

PMID41898705
PMCPMC13026499

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.