Evidence mapPaperPMID 41899162Full record

ReviewJournal of clinical medicine2026

Surgical Necrotising Enterocolitis (S-NEC): Where We Stand Today: A Narrative Review.

Maria Manousi, Dionysios Dellaportas, Konstantinos Nastos, Christina Siouli, Yvelise De Verney, Anastasia Dimopoulou, Nikolaos Zavras

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maria ManousiFirst Department of Pediatric Surgery, "Pan. & Aglaia Kyriakou" Children's Hospital, 11526 Athens, Greece.ORCID 0009-0006-9411-8852
Dionysios DellaportasThird Department of Surgery, Attikon University Hospital, National and Kapodistrian University of Athens, 12462 Athens, Greece.ORCID 0000-0003-3419-4862
Konstantinos NastosThird Department of Surgery, Attikon University Hospital, National and Kapodistrian University of Athens, 12462 Athens, Greece.
Christina SiouliFirst Department of Pediatric Surgery, "Aghia Sophia" Children's Hospital, 11527 Athens, Greece.
Yvelise De VerneyFirst Department of Pediatric Surgery, "IASO" Maternity and Children's Hospital, 15123 Athens, Greece.ORCID 0000-0002-0100-2257
Anastasia DimopoulouFirst Department of Pediatric Surgery, "Aghia Sophia" Children's Hospital, 11527 Athens, Greece.ORCID 0000-0002-5021-5152
Nikolaos ZavrasDepartment of Pediatric Surgery, School of Medicine, Attikon University Hospital, National and Kapodistrian University of Athens, 12462 Athens, Greece.ORCID 0000-0003-2546-4533

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Surgical necrotising enterocolitis (NEC) continues to carry significant morbidity and mortality in preterm and very-low-birth-weight infants. This review presents up-to-date evidence to guide the shift from medical to surgical treatment and to improve management during and after surgery. Need for surgery is best anticipated through dynamic clinical assessment, supported by laboratory markers of systemic inflammation or ischemia and targeted imaging, while pneumoperitoneum remains the sole absolute indication for immediate intervention. In infants without perforation, the timing of surgery remains challenging: delayed surgery after clinical deterioration worsens long-term outcomes, whereas very early surgery often reflects severe disease leading to greater bowel loss, highlighting the need for carefully timed intervention after brief stabilisation. Laparotomy remains the cornerstone of surgical management, with peritoneal drainage serving as a temporising option for the most unstable infants and laparoscopy emerging as a feasible adjunct. Long-term complications, including strictures, short bowel syndrome, neurodevelopmental impairment, bronchopulmonary dysplasia and severe retinopathy of prematurity highlight the need for better predictive tools, enhanced imaging of bowel viability, and rigorous nutritional support, while long-term quality-of-life outcomes remain insufficiently studied.

Indexed as

artificial intelligencebiomarkersclinicaldecision-makinglaparoscopylaparotomynecrotising enterocolitissurgerytime factorsultrasonography

Identifiers

PMID41899162
PMCPMC13027178

What Socratic holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.