ReviewCurrent issues in molecular biology2026
Role of Growth Hormone (GH) and Other Somatotropic Axis Elements in Retinal Neuroprotection.
Review in Current issues in molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
3 authors.
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Abstract
Various pathological conditions can result in retinal degeneration and, in extreme cases, blindness. Unfortunately, current treatments for many of these conditions are not effective, and ongoing research encounters numerous obstacles due to the complex nature of these diseases, which involve multiple simultaneous mechanisms that cannot be controlled by a single factor. Therefore, there is an urgent need to propose and test new molecules that could exert protective effects at multiple levels. Traditionally, growth hormone (GH) has been viewed as a detrimental factor contributing to develop retinopathies. However, recent investigation has debunked this notion, revealing that GH treatment exerts strong neuroprotective effects during retinal injury. It is crucial to recognize that these actions are not exclusive to GH, since other related molecules may also be involved. Therefore, it is important to collect relevant existing evidence regarding GH axis translational research in order to understand its potential as a therapeutic option for retinal degeneration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.