PSMB8 as a Core Target Mediating the Anti-Hepatocellular Carci-Noma Activity of Lingonberry (

Liangyu Zhu, Zhi Zhang, Yandong Zhang, Dianwen Wei, Zhenyu Wang, Liping Zhou

Abstract read

In one paragraph

Article in Current issues in molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Liangyu ZhuDepartment of Natural Plant Functional Products, Heilongjiang Academy of Sciences Institute of Natural Resources and Ecology, Harbin 150040, China.ORCID 0000-0001-6094-4845

Zhi ZhangDepartment of Forestry, Northeast Forestry University, Harbin 150040, China.

Yandong ZhangDepartment of Life Sciences and Food Engineering, Hebei University of Engineering, Handan 056038, China.

Dianwen WeiDepartment of Natural Plant Functional Products, Heilongjiang Academy of Sciences Institute of Natural Resources and Ecology, Harbin 150040, China.

Zhenyu WangDepartment of Food Science and Engineering, Harbin Institute of Technology, Harbin 150090, China.

Liping ZhouDepartment of Natural Plant Functional Products, Heilongjiang Academy of Sciences Institute of Natural Resources and Ecology, Harbin 150040, China.

Funding

Heilongjiang Postdoctoral Science Foundation LBH-Z23264National Key Research and Development Programme of China during the 14th Five-Year Plan period 2022YFD1600502-16Outstanding Young Scientists Project of Heilongjiang Academy of Sciences JQ2024ZR02Scientific Research Business Expense Project of Heilongjiang Provincial Affiliated Research Institutes CZKYF2024-1-C009

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is a highly malignant tumour with a poor prognosis and few effective treatment options. Development of resistance to conventional therapies and occurrence of severe side effects highlight the urgent need for novel, low-toxicity interventions. Natural products are promising candidates for HCC drug development thanks to their multi-target activity and favourable safety profiles. Previous studies reported that Lingonberry extract, a bioactive natural product, inhibits proliferation of HepG

Indexed as

apoptosishepatocellular carcinoma (HCC)HepG2lingonberry extractnatural productPSMB8xenograft model

Identifiers

PMID41899474

DOI10.3390/cimb48030323

PMCPMC13025438

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.