ReviewInternational journal of environmental research and public health2026
Climate Change, Epigenetics, Microbiota, and Health.
Review in International journal of environmental research and public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The acceleration of climate change poses a growing threat to human health, particularly by exacerbating non-communicable diseases (NCDs) such as cardiovascular and respiratory conditions. Rising global temperatures amplify air pollution and environmental toxins, disproportionately affecting vulnerable populations. This narrative review explores the complex pathways linking climate-related environmental stressors to adverse health outcomes, focusing on the intermediary roles of epigenetic modifications and alterations in the microbiota. Epigenetic processes, including DNA methylation and histone modifications, may mediate how environmental exposures influence gene expression and disease susceptibility. Concurrently, changes in microbiota composition induced by pollutants and temperature fluctuations can promote inflammatory responses and immune dysfunction. Elucidating these molecular mechanisms is essential for developing targeted interventions and adaptive strategies to mitigate the health impacts of climate change. This review underscores the importance of identifying epigenetic and microbiota-based biomarkers for early risk stratification and for informing public health prevention and adaptation policies. A transdisciplinary approach, grounded in the One Health framework, is critical to addressing the growing burden of climate-sensitive diseases and reducing health inequalities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.