Evidence mapPaperPMID 41900192Full record

ReviewMicromachines2026

Stimuli-Responsive Nanomaterial-Based Biosensor Structures for Wound Care: pH, ROS, and Temperature Sensing Strategies.

Anita Ioana Visan, Adrian Birnaz, Irina Negut

Abstract readReview
In one paragraph

Review in Micromachines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anita Ioana VisanNational Institute for Laser, Plasma and Radiation Physics (INFLPR), Atomiştilor 409, 077125 Magurele, Romania.ORCID 0000-0003-0539-4160
Adrian BirnazCenter for Nanotechnology and Nanosensors, Department of Microelectronics and Biomedical Engineering, Technical University of Moldova, 168 Ștefan cel Mare Avenue, MD-2004 Chisinau, Moldova.ORCID 0000-0002-2906-7255
Irina NegutNational Institute for Laser, Plasma and Radiation Physics (INFLPR), Atomiştilor 409, 077125 Magurele, Romania.ORCID 0000-0003-4038-7548

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic and infected wounds remain a major clinical challenge due to their dynamic microenvironments and the lack of real-time diagnostic feedback in conventional dressings. Recent advances in stimuli-responsive nanomaterial-based biosensors have enabled the development of smart wound-care systems capable of continuous monitoring and on-demand therapeutic intervention. This review systematically summarizes progress in nanomaterial-enabled wound biosensing strategies, with a focus on pH, reactive oxygen species, and temperature nanosensors, which serve as key indicators of infection, inflammation, and healing status. We discuss the sensing mechanisms and functional roles of diverse nanomaterials. A particular focus is placed on emerging multimodal and theranostic platforms which integrate biochemical and physical sensing with controlled drug release, photothermal or photodynamic therapy, and redox regulation. These systems represent a shift from passive wound monitoring toward closed-loop, adaptive wound management. Also, future perspectives are outlined, highlighting the convergence of nanomaterials, self-powered electronics, and intelligent data processing as a pathway toward personalized and precision wound care.

Indexed as

smart wound biosensorsstimuli-responsive nanomaterialstheranostic wound care

Identifiers

PMID41900192
PMCPMC13027940

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.