Evidence map›Paper›PMID 41900348›Full record

ArticleMicroorganisms2026

Serum Proteomics Provides Novel Biomarkers of Inflammation, Tissue Injury, and Therapeutic Response in Experimental Chagas Disease.

Eloan Mendes Vieira, Camilo Elber Vital, Paula Melo de Abreu Vieira, Lorena Cera Bandeira, Luciana da Fonseca Medeiros, Nívia Carolina Nogueira Paiva, William de Castro Borges, Cláudia Martins Carneiro

Abstract read
In one paragraph

Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eloan Mendes VieiraLaboratory of Immunopathology, Nucleus of Biological Sciences Research, Institute of Exact and Biological Sciences, Federal University of Ouro Preto, Ouro Preto 35400-000, Brazil.ORCID 0000-0002-2234-6999
Camilo Elber VitalEnzymology and Proteomics Laboratory, Department of Biological Sciences, Nucleus of Biological Sciences Research, Institute of Exact and Biological Sciences, Federal University of Ouro Preto, Ouro Preto 35400-000, Brazil.
Paula Melo de Abreu VieiraLaboratory of Morphopathology, Department of Biological Sciences, Nucleus of Biological Sciences Research, Institute of Exact and Biological Sciences, Federal University of Ouro Preto, Ouro Preto 35400-000, Brazil.ORCID 0000-0001-7033-7686
Lorena Cera BandeiraLaboratory of Immunopathology, Nucleus of Biological Sciences Research, Institute of Exact and Biological Sciences, Federal University of Ouro Preto, Ouro Preto 35400-000, Brazil.
Luciana da Fonseca MedeirosLaboratory of Immunopathology, Nucleus of Biological Sciences Research, Institute of Exact and Biological Sciences, Federal University of Ouro Preto, Ouro Preto 35400-000, Brazil.ORCID 0000-0003-0999-0699
Nívia Carolina Nogueira PaivaLaboratory of Immunopathology, Nucleus of Biological Sciences Research, Institute of Exact and Biological Sciences, Federal University of Ouro Preto, Ouro Preto 35400-000, Brazil.
William de Castro BorgesEnzymology and Proteomics Laboratory, Department of Biological Sciences, Nucleus of Biological Sciences Research, Institute of Exact and Biological Sciences, Federal University of Ouro Preto, Ouro Preto 35400-000, Brazil.
Cláudia Martins CarneiroLaboratory of Immunopathology, Nucleus of Biological Sciences Research, Institute of Exact and Biological Sciences, Federal University of Ouro Preto, Ouro Preto 35400-000, Brazil.ORCID 0000-0002-6002-857X

Funding

Fundação de Amparo a Pesquisa de Minas Gerais - FAPEMIG APQ-01944-21
6 · The paper itself

Abstract

Chagas disease remains a major public health challenge and still lacks reliable serum biomarkers capable of accurately reflecting disease progression and therapeutic response. Here, we performed a quantitative label-free serum proteomic analysis in a murine model infected with two

Indexed as

benznidazole responseChagas diseasedrug resistanceinflammatory biomarkersserum proteomicsTrypanosoma cruzi

Identifiers

PMID41900348
PMCPMC13028842

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.