Evidence mapPaperPMID 41900775Full record

ArticlePharmaceutics2026

A Physiologically Based Pharmacokinetic and Pharmacodynamic (PBPK/PD) Model of Dapagliflozin in Type 2 Diabetes Mellitus: The Effect of Dosing, Hepatorenal Impairment, and Food.

Nike Nemitz, Michelle Elias, Matthias König

Abstract read
In one paragraph

Article in Pharmaceutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nike NemitzFaculty of Life Science, Institute for Biology, Systems Medicine of the Liver, Humboldt-Universität zu Berlin, Unter den Linden 6, 10099 Berlin, Germany.ORCID 0009-0006-4892-3279
Michelle EliasFaculty of Life Science, Institute for Biology, Systems Medicine of the Liver, Humboldt-Universität zu Berlin, Unter den Linden 6, 10099 Berlin, Germany.ORCID 0009-0005-7959-3164
Matthias KönigFaculty of Life Science, Institute for Biology, Systems Medicine of the Liver, Humboldt-Universität zu Berlin, Unter den Linden 6, 10099 Berlin, Germany.ORCID 0000-0003-1725-179X

Funding

Bundesministerium für Forschung, Technologie und Raumfahrt 031L0304BGerman Research Foundation (DFG) 436883643German Research Foundation (DFG) 465194077
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

dapagliflozinpersonalized medicinepharmacodynamicspharmacokineticsphysiologically based pharmacokinetic/pharmacodynamic model (PBPK/PD)type 2 diabetes mellitus

Identifiers

PMID41900775
PMCPMC13028959

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.