Evidence map›Paper›PMID 41900880›Full record

ArticlePharmaceutics2026

pH-Responsive ZIF-8 Precisely Induces Apoptosis of Oral Squamous Cell Carcinoma over Orofacial Mesenchymal Stem Cells.

Jessica Hao, Mehrnaz Zakershahrak, Peter Ly, Xiaobin Huang, Kunfeng Sun, Shilan Zhang, Fusun Ozer, Chider Chen

Abstract read
In one paragraph

Article in Pharmaceutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jessica HaoDepartment of Oral & Maxillofacial Surgery & Pharmacology, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-9741-3113
Mehrnaz ZakershahrakDepartment of Oral & Maxillofacial Surgery & Pharmacology, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0009-0004-3876-0117
Peter LyDepartment of Biology, College of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-7386-9140
Xiaobin HuangDepartment of Oral & Maxillofacial Surgery & Pharmacology, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Kunfeng SunDepartment of Oral & Maxillofacial Surgery & Pharmacology, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-3874-8909
Shilan ZhangDepartment of Oral & Maxillofacial Surgery & Pharmacology, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Fusun OzerDepartment of Preventive and Restorative Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0003-1213-4957
Chider ChenDepartment of Oral & Maxillofacial Surgery & Pharmacology, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0003-2899-1208

Funding

Stromal Effects in Head and Neck Squamous Cell CarcinomaR01CA288366 · NCI · UNIVERSITY OF PENNSYLVANIA · PI Chi-Der Chen · 2024 to 2026
$1.1M
Repurposing Ferumoxytol Nanoparticles to Promote Orofacial Stem Cell Function for AutotherapiesR21DE033128 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI CHEN, CHI-DER · 2024 to 2025
$447k
NCI NIH HHS R01 CA288366NIDCR NIH HHS R21 DE033128NIH Common Fund R01CA288366NIH Common Fund R21DE033128
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

apoptosisdrug deliverymesenchymal stem/stromal cells (MSCs)oral squamous cell carcinoma (OSCC)zeolite imidazolate framework-8 (ZIF-8)

Identifiers

PMID41900880
PMCPMC13029682

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.