Simvastatin Enhances Stem Cell Osteogenesis and Reduces Peri-Implant Bone Loss: An In Vitro and a Randomized Clinical Study.

Asmaa Saleh, Shereen N Raafat, Sherihan Ahmed Sayed, Mohamed Shamel, Sherif Shafik El Bahnasy, Sara F El Shafei

Abstract read

In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Diosmin-Capped Silver Nanoparticles Promote Osteogenic Differentiation of Human Periodontal Ligament Stem Cells: Box-Behnken Optimization and in vitro Evaluation.International journal of nanomedicine · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Asmaa SalehDepartment of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah Bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.ORCID 0000-0002-6286-319X

Shereen N RaafatDepartment of Pharmacology, Faculty of Dentistry, The British University in Egypt, Al Sherouk City 11837, Cairo, Egypt.

Sherihan Ahmed SayedDepartment of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, Galala University, New Galala City 43511, Suez, Egypt.ORCID 0000-0002-4681-0338

Mohamed ShamelDepartment of Oral Biology, Faculty of Dentistry, The British University in Egypt, Al Sherouk City 11837, Cairo, Egypt.ORCID 0000-0003-0061-5163

Sherif Shafik El BahnasyOral and Maxillofacial Radiology Department, Faculty of Dentistry, The British University in Egypt, Al Sherouk City 11837, Cairo, Egypt.ORCID 0000-0003-2380-2519

Sara F El ShafeiDepartment of Removable Prosthodontics, Faculty of Dentistry, The British University in Egypt, Al Sherouk City 11837, Cairo, Egypt.ORCID 0000-0002-5060-8941

Funding

Princess Nourah bint Abdulrahman University PNURSP2025R141

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

bone regenerationdental-implantsPRFsimvastatinstem cells

Identifiers

PMID41901215

DOI10.3390/ph19030368

PMCPMC13029674

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.