Evidence mapPaperPMID 41901302Full record

ReviewPharmaceuticals (Basel, Switzerland)2026

Anti-Inflammatory Activity of Cyclic Imide Derivatives.

Aleksandra Redzicka, Beata Tylińska, Anna Wójcicka

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aleksandra RedzickaDepartment of Medicinal Chemistry, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wrocław, Poland.ORCID 0000-0003-1508-8327
Beata TylińskaDepartment of Organic Chemistry and Pharmaceutical Technology, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211A, 50-556 Wrocław, Poland.ORCID 0000-0003-2094-6533
Anna WójcickaDepartment of Organic Chemistry and Pharmaceutical Technology, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211A, 50-556 Wrocław, Poland.ORCID 0000-0001-5057-211X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Imide derivatives constitute an interesting group of compounds exhibiting broad biological activity. Structures containing the imide moiety [-CO-N(R)-CO-] occur in both natural and synthetic compounds. Several drugs containing an imide moiety are in therapeutic use. In this review, we present the structures and describe the effects of cyclic imide derivatives, which primarily exhibit anti-inflammatory activity. Some of the presented derivatives have been studied in detail, and their additional analgesic, anticancer, and antibacterial effects have been described. The relative neuroprotective properties of imide derivatives are also described, as are reports of their effect on lowering cholesterol and triglyceride levels. In this review, we discuss monocyclic imide derivatives (succinimide, glutarimide, maleimide, and hydantoin), bicyclic derivatives (e.g., phthalimide), and polycyclic imides.

Indexed as

anti-inflammatory activitycyclic imidescyclooxygenase (COX)glutarimideshydantoinsinterleukin-6 (IL-6)lipoxygenase (LOX)maleimidesnaphthalimidesphthalimidessuccinimidestumor necrosis factor-α (TNF-α)

Identifiers

PMID41901302
PMCPMC13029124

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.