Evidence mapPaperPMID 41901560Full record

ReviewMedicina (Kaunas, Lithuania)2026

Pancreatic Neuroendocrine Tumors: From Benchside to Surgical Treatment.

Giovanni Conzo, Federico Maria Mongardini, Maddalena Paolicelli, Michele Klain, Giuseppe Bellastella, Alessandra Conzo, Zhou Bo, Eduardo Lanza, Leandra Piscopo, Renato Patrone

Abstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Giovanni ConzoDivision of General, Oncological, Mini-Invasive and Obesity Surgery, University of Study of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Federico Maria MongardiniDivision of General, Oncological, Mini-Invasive and Obesity Surgery, University of Study of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0003-4980-0335
Maddalena PaolicelliDivision of General, Oncological, Mini-Invasive and Obesity Surgery, University of Study of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0009-0005-5057-1981
Michele KlainDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", 80138 Naples, Italy.ORCID 0000-0001-9505-7306
Giuseppe BellastellaDepartment of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-4748-321X
Alessandra ConzoDivision of General, Oncological, Mini-Invasive and Obesity Surgery, University of Study of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Zhou BoDepartment of Hepatobiliary and Pancreatic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Eduardo LanzaDivision of General, Oncological, Mini-Invasive and Obesity Surgery, University of Study of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Leandra PiscopoRadiology Department of Surgery, Medicine and Pharmacy, University of Sassari, 07100 Sassari, Italy.ORCID 0009-0000-5487-1360
Renato PatroneHepatobiliary Surgical Oncology Unit, Istituto Nazionale Tumori IRCCS Fondazione Pascale-IRCCS di Napoli, 80131 Naples, Italy.ORCID 0000-0002-6969-4157

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic neuroendocrine tumors (pNETs) are rare, clinically heterogeneous neoplasms with rising incidence linked to improved diagnostics. This review examines pNET management, addressing epidemiology, classification, diagnosis, treatment, and emerging therapies. Epidemiologically, pNETs show higher prevalence in Western populations, with emerging associations to metabolic disorders. The 2022 WHO classification highlights distinct prognoses for well-differentiated NETs versus poorly differentiated NECs, guided by Ki-67 and mitotic indices. Non-functional tumors often present late, while functional variants manifest hormonal syndromes, necessitating tailored approaches. Advanced imaging (contrast-enhanced CT/MRI,

Indexed as

Neuroendocrine TumorsPancreatic NeoplasmsHumansmininvasive surgerymolecular targeted therapymultidisciplinary managementpancreatic neuroendocrine tumorspeptide receptor radionuclide therapyquality of life

Identifiers

PMID41901560
PMCPMC13027795

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.