ReviewViruses2026
Molecular Maneuvers and Host Sabotage: A Comprehensive Review of CSFV's Multifaceted Strategies to Subvert Immune Defenses and Cellular Metabolism.
Review in Viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Classical swine fever virus (CSFV) remains a significant threat to the global swine industry, causing a highly contagious and often fatal disease in pigs. This review comprehensively examines the molecular biology of CSFV and the intricate mechanisms it employs to establish infection. We detail the structure and functions of viral proteins, highlighting their roles in virus entry, replication, and immune evasion. A major focus is placed on the virus-host interaction, specifically how CSFV subverts host innate immune responses and hijacks critical cellular processes, including metabolism and cell death pathways. The virus strategically manipulates host cell death programs (apoptosis, mitophagy, necroptosis) and exploits intracellular transport systems to promote its propagation. Furthermore, we summarize recent advances in understanding the cellular receptors involved in CSFV entry and the role of exosomes in viral spread. This synthesis of current knowledge aims to provide a deeper insight into the pathogenesis of CSFV and identify potential vulnerabilities that could be targeted for the development of novel antiviral strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.