ReviewCurrent opinion in neurobiology2026
Complementary influences of noradrenaline and dopamine in orchestrating a motivated social behavior.
Review in Current opinion in neurobiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- A prolactin-receptive neural circuit drives maternal interactions with pups in mice.Science advances · 2026Article
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Authors and funding
1 author.
Funding
Abstract
Noradrenaline (NA) and dopamine (DA) modulate motivated behavior, yet their contributions to social interactions are difficult to disentangle due to overlapping responses and the unstructured nature of free behavior. We address this challenge by using a natural and spontaneous maternal behavior called 'pup retrieval'. Here, we synthesize recent work demonstrating that NA and DA play complementary but temporally dissociable roles during pup retrieval. The NA released from the locus coeruleus (LC) invigorates ongoing retrieval behavior, mobilizing downstream circuits to drive goal-directed action in response to pup distress. In contrast, dopamine released from the ventral tegmental area (VTA) improves future retrieval behavior by reducing latency across trials. These findings suggest a model in which NA governs the execution of the current caregiving episode, while DA updates motivational value to optimize future maternal responses. This framework may generalize to other forms of social and affiliative behavior requiring coordination between imminent action and long-term learning.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.