ArticleZhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences2026
[Association of metabolic syndrome and its components with gout: an analysis based on a large-scale health survey database].
Article in Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesTo investigate the association of metabolic syndrome (MetS) and its components with gout.
methodsThis study utilized data from 28 130 adults aged ≥18 years in the National Health and Nutrition Examination Survey (NHANES) 2007-2018, among whom 1279 were identified as gout patients. Logistic regression was used to assess the associations of MetS and its components with gout. Restricted cubic spline (RCS) models were employed to examine non-linear dose-response relationships between metabolic indicators and gout. Subgroup analyses were performed by age, sex, and body mass index (BMI), with interaction effects evaluated using the Wald test by including multiplicative interaction terms in the logistic regression models.
resultsThe prevalence of MetS was substantially higher in individuals with gout than in those without (66.9%
conclusionsMetS is independently associated with gout, exhibiting significant non-linear dose-response characteristics and population heterogeneity.
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