Evidence map›Paper›PMID 41906187›Full record

ArticleBioMed research international2026

Gene Variants Associated With Individual Sensitivity for Taste Changes After the COVID-19 Infection.

Lejla Pojskic, Ivona Kenjic, Belmina Saric Medic, Nikolina Tomic, Naris Pojskic, Jasmin Ramic, Naida Lojo Kadric

Abstract read
In one paragraph

Article in BioMed research international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lejla PojskicInstitute for Genetic Engineering and Biotechnology, University of Sarajevo, Sarajevo, Bosnia and Herzegovina, unsa.ba.ORCID https://orcid.org/0000-0003-2260-318X
Ivona KenjicDepartment of Biology, Faculty of Science, University of Sarajevo, Sarajevo, Bosnia and Herzegovina, unsa.ba.ORCID https://orcid.org/0009-0004-5638-0775
Belmina Saric MedicInstitute for Genetic Engineering and Biotechnology, University of Sarajevo, Sarajevo, Bosnia and Herzegovina, unsa.ba.ORCID https://orcid.org/0000-0001-8593-4678
Nikolina TomicInstitute for Genetic Engineering and Biotechnology, University of Sarajevo, Sarajevo, Bosnia and Herzegovina, unsa.ba.ORCID https://orcid.org/0000-0001-9529-3384
Naris PojskicInstitute for Genetic Engineering and Biotechnology, University of Sarajevo, Sarajevo, Bosnia and Herzegovina, unsa.ba.ORCID https://orcid.org/0000-0001-6765-2976
Jasmin RamicInstitute for Genetic Engineering and Biotechnology, University of Sarajevo, Sarajevo, Bosnia and Herzegovina, unsa.ba.
Naida Lojo KadricInstitute for Genetic Engineering and Biotechnology, University of Sarajevo, Sarajevo, Bosnia and Herzegovina, unsa.ba.ORCID https://orcid.org/0000-0002-0534-1336

Funding

Ministry of Science, Higher Education and Youth of Sarajevo Canton 27-02-11-41250-40/21
6 · The paper itself

Abstract

Human gustatory function is a complex trait combining taste, smell, and touch required for the safety and quality assessment of ingested food. Taste dysfunction is one of the most prominent symptoms of COVID-19 that was reversible in most cases, but some patients reported permanent changes in their perception of different food sources. This symptom brought attention to the complexity of the regulation of smell and taste and their potential use in diagnostics and treatment of acute and chronic taste disorders. We investigated the genetic association of candidate genes with SARS-CoV-2 infection-related dysgeusia. A total of 96 individuals with confirmed virus infection were divided into groups according to the presence of self-reported taste dysfunction and genotyped using a custom Illumina gene panel. Out of 18 functionally related taste genes, statistically significant differences were observed for HCN4 variants c∗2393C > G (p = 0.013) and c.2556G > A (p = 0.026), PLCB2 variants c.3037-55T > C (p = 0.019) and c.582+958_582+959inv (p = 0.021), and TAS1R1 variant c.1594+41G > A (p = 0.03), which indicate possible association to taste dysfunction in response to virus infection.

Indexed as

COVID-19DysgeusiaTasteTaste DisordersAdultAgedFemaleGenetic VariationGenotypeHumansMaleMiddle AgedPolymorphism, Single NucleotideReceptors, G-Protein-CoupledSARS-CoV-2Receptors, G-Protein-Coupledtaste receptors, type 1COVID-19genetic propensitypostinfectious dysgeusiasmell and taste dysfunctiontaste factors

Identifiers

PMID41906187
PMCPMC13140813

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.