ArticleEuropean journal of immunology2026
Post-Acute Sequelae Patients with Severe COVID-19 History Show a Prolonged Inflammatory, Vascular Injury Pattern.
Article in European journal of immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
SARS-CoV-2 infection can lead to persistent symptoms (i.e., long/post-COVID), especially in unvaccinated individuals. Little is known about the sustained impact of acute severe COVID-19 on immune signatures and long/post-COVID symptoms, often associated with cardiovascular events and pulmonary impairment. The longitudinal cohort (LC) was obtained from N = 46 patients with previous severe COVID-19 and prior to SARS-CoV-2 vaccination, collected over 5 visits up to 12 months after discharge (n = 139). Long/post-COVID status was assessed by lung function and fatigue scores. Blood was analysed regarding immune cell profiles, SARS-CoV-2 antibodies, and autoantigens. LC patients were compared with 39 acute severe COVID-19 ICU patients and 28 unexposed pre-pandemic donors (UE) and correlated with clinical parameters. LC patients exhibited long-term decreased CD4
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