Evidence map›Paper›PMID 41906925›Full record

ArticlePlant, cell & environment2026

Rhizobacteria-Induced Systemic Priming Against Fungal Pathogens Involves Hydroxycinnamic Acid Amides.

Mackenzie Eli William Loranger, Wolfgang Moeder, Hyunsuh Lee, David K Liscombe, Eric Déziel, Keiko Yoshioka

Abstract read
In one paragraph

Article in Plant, cell & environment, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mackenzie Eli William LorangerDepartment of Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0009-0000-2647-7534
Wolfgang MoederDepartment of Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0003-3889-6183
Hyunsuh LeeDepartment of Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada.
David K LiscombeVineland Research & Innovation Centre, Vineland Station, Ontario, Canada.
Eric DézielCentre Armand-Frappier Santé Biotechnologie, Institut National de la Recherche Scientifique (INRS), Laval, Quebec, Canada.ORCID https://orcid.org/0000-0002-4609-0115
Keiko YoshiokaDepartment of Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-3797-4277

Funding

Natural Sciences and Engineering Research Council of Canada
6 · The paper itself

Abstract

The rhizosphere, a narrow region of soil surrounding roots, contains diverse microorganisms with a composition that is distinct from the surrounding soil. Some rhizosphere bacteria can trigger a heightened state of immunity in the whole plant, termed Induced Systemic Resistance (ISR). To understand the mechanisms behind this enhanced resistance we investigated the metabolic profile of tomato plants treated with Pseudomonas defensor WCS374r and Bacillus velezensis VFb49, bacterial strains know to elicit ISR in tomato, using an untargeted approach, from which we identified a set of differentially accumulated metabolites (DAMs). We show that some of these metabolites-the hydroxycinnamic acid amides (HCAAs) caffeoyl putrescine and feruloyl putrescine-exhibit direct antimicrobial properties against two fungal pathogens, Botrytis cinerea and Fusarium virguliforme. Further, we show that in Arabidopsis thaliana agmatine coumaroyl transferase (AtACT) is induced by both bacteria and is required for resistance to B. cinerea. The apoplastic location of these compounds is also crucial for their function as the multidrug and toxin extrusion (MATE) transporter, AtDTX18, is essential for the resistance phenotype. Overall, this work offers novel insights into the mechanism of ISR, suggesting that the accumulation of HCAAs is one of the factors conferring enhanced resistance to pathogen infection.

Indexed as

AmidesBacillusCoumaric AcidsPlant DiseasesPseudomonasSolanum lycopersicumArabidopsisBotrytisFusariumPlant Systemic Acquired ResistanceRhizosphereAmidesCoumaric AcidsBacillus velezensishydroxycinnamic acid amidesinduced systemic resistanceISRmetabolomicsplant immunityPseudomonas defensor WCS374rrhizosphereSolanum lycopersicum

Identifiers

PMID41906925
PMCPMC13353667

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.