Advancing biomedical technology through multifunctional porphyrin-based MOFs: design principles, applications, and biosafety evaluations.

Tushuai Li, Wenxue Sun, Hongying Pan, Qi Tang, Lanxin Geng, Jin Liu, Guangfu Liao, Yanhua Zhang

Abstract readReview

In one paragraph

Review in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tushuai LiSchool of Biology and Food Engineering, Suzhou University of Technology, Suzhou, Jiangsu, 215500, China.

Wenxue SunTranslational Pharmaceutical Laboratory, Jining NO.1 People's Hospital, Shandong First Medical University, Jining, 272000, China.

Hongying PanSchool of Biology and Food Engineering, Suzhou University of Technology, Suzhou, Jiangsu, 215500, China.

Qi TangSchool of Biology and Food Engineering, Suzhou University of Technology, Suzhou, Jiangsu, 215500, China.

Lanxin GengSchool of Biology and Food Engineering, Suzhou University of Technology, Suzhou, Jiangsu, 215500, China.

Jin LiuSchool of Biology and Food Engineering, Suzhou University of Technology, Suzhou, Jiangsu, 215500, China.

Guangfu LiaoCollege of Materials Engineering, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.

Yanhua ZhangDepartment of Obstetrics and Gynecology, Binhai County People's Hospital, Yancheng, Jiangsu, 224500, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porphyrin-based metal-organic frameworks (MOFs) have a great deal of promise for widespread use in biomedical and nanomedical fields because of their exceptional structural and functional properties, good biosafety and low toxicity, and intrinsic biodegradability. This review systematically outlines the design principles of porphyrin-based MOFs and highlights their latest developments in a variety of biomedical applications, including cancer therapy, antibacterial treatment, wound healing, and biosensors. Subsequently, we critically examine their biosafety and toxicity aspects. Finally, we detail the current state of the art, ongoing challenges, and future prospects for the emerging materials in biomedicine. With continued research efforts, multifunctional porphyrin-based MOFs have great potential for future clinical translation.

Indexed as

Antibacterial therapyBiosafety and toxicity evaluationsBiosensorsCancer treatmentPorphyrin-based metal–organic frameworksWound healing

Identifiers

PMID41907112

DOI10.1016/j.mtbio.2026.103025

PMCPMC13018993

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.