Evidence map›Paper›PMID 41907153›Full record

ReviewPatient preference and adherence2026

Eighteen Years of Measuring Treatment Satisfaction in Clinical Research: A Scoping Review of Instruments and Contexts of Use.

Carolina Navas, Inigo Valiente-Alandi, Laura Luque-Aguilera, Ana Maria Rodriguez-Leboeuf

Abstract readReview
In one paragraph

Review in Patient preference and adherence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Carolina NavasPatient-Centered Solutions, IQVIA, Madrid, Spain.ORCID 0000-0002-3717-398X
Inigo Valiente-AlandiPatient-Centered Solutions, IQVIA, Madrid, Spain.
Laura Luque-AguileraPatient-Centered Solutions, IQVIA, Madrid, Spain.
Ana Maria Rodriguez-LeboeufPatient-Centered Solutions, IQVIA, Madrid, Spain.ORCID 0000-0001-6335-3223

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Despite the widespread use of Patient Reported Outcomes (PRO) instruments to assess treatment satisfaction in clinical trials and academic research, a comprehensive review mapping these tools across therapeutic areas has been lacking. This scoping review addresses this gap by examining the application of PRO instruments over the past 18 years. Methods: Following Arksey and O'Malley's framework and mixed-method principles, we searched Ovid MEDLINE and Ovid EMBASE from 2004 to June 2022. Data extraction was structured according to review objectives and key domains. Results: Of 3,497 articles retrieved, 1,398 studies reported using PRO instruments for treatment satisfaction. The most common therapeutic areas were endocrine, nutrition, and metabolic disorders, followed by mental and behavioral conditions. Most studies were conducted in academic settings (53.1%) or Phase III clinical trials (27.5%). The Treatment Satisfaction Questionnaire for Medication (TSQM) was the most frequently used generic instrument, while the Diabetes Treatment Satisfaction Questionnaire (DTSQ) was the leading disease-specific tool. Many instruments lacked psychometric validation, limiting comparability. Conclusion: PRO instruments for treatment satisfaction are primarily used in chronic disease contexts. Their widespread adoption underscores the need for validated tools to ensure robust, comparable data and support better patient outcomes.

Indexed as

academic researchclinical trialsDTSQPROtreatment satisfactionTSQM

Identifiers

PMID41907153
PMCPMC13031261

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.