ArticleDrug and alcohol dependence reports2026
Perceived risk of substance use and associations with early experimentation: A latent profile analysis using ABCD study data.
Article in Drug and alcohol dependence reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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10 authors.
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Abstract
Objective: The current study aims to determine heterogenous latent profiles of substance use perceived harm and examine the concurrent associations between profiles and substance use experimentation. Methods: We used data from the Adolescent Brain Cognitive Development Results: A four-profile solution fit the data best. The four profiles included participants in 1) high harm perceptions across all substances, 2) low harm perceptions across all substances, 3) moderate harm perceptions across all substances, and 4) selective high-harm perceptions for some substances. Those in the low harm profile (AOR = 4.99, p < .01) and selective high-harm profile (AOR = 3.04, p < .05) were more likely to report puffing tobacco compared to the high harm profile. Also, those in the moderate harm profile (AOR = 1.36, p < .05) and those in the selective high-harm profile (AOR = 1.56, p < .001) were more likely to report sipping alcohol compared to the high harm group. Conclusion: The four-profile solution illustrates meaningful heterogeneity in how youth perceive substance-related harm, suggesting the need for more tailored prevention approaches rather than one-size-fits-all messaging considering that even partial recognition of risk may not fully protect against experimenting with substances.
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