ArticleJournal of inflammation research2026
The Evolving Research Landscape of Radiation Enteritis Prevention and Management: A Data-Driven Analysis.
Article in Journal of inflammation research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Radiation enteritis (RE) is a common complication following radiotherapy, adversely affecting patient prognosis and quality of life. This study aims to analyze the evolving research landscape of RE prevention and management through a data-driven approach, aiming to delineate the developmental trajectory, identify research hotspots and emerging frontiers, and forecast future trends in RE prevention and management. Methods: We conducted a data-driven analysis of relevant publications retrieved from the Web of Science Core Collection (2005-2024). Visualization tool was employed to examine collaboration networks, research hotspots, and trends. A supplementary search in PubMed was conducted to identify related clinical trials. Results: A total of 594 publications indexed in the Web of Science Core Collection were subjected to a data-driven visual analysis, while a supplementary search in PubMed identified 51 clinical trials to further clarify clinical research status. In this field, the main research topics include prostate cancer, rectal cancer, and cervical cancer, and the main research hotspots include studies on the pathological mechanism of RE, as well as research on the application of conformal radiotherapy, argon plasma coagulation, hyperbaric oxygen therapy, and microbiota transplantation in the prevention and management of RE. Early burst keywords mainly include "conformal radiotherapy", "sucralfate", "home parenteral nutrition", "intensity modulated radiotherapy", and "hyperbaric oxygen therapy". In the past three years, the burst keywords in the outbreak period mainly include "efficacy", "chemoradiation", "stem cells", and "transplantation". Conclusion: This study reveals that the field has gradually shifted over the past two decades from an initial focus on pathological mechanisms and symptom management toward etiological therapy, with current research frontiers centered on therapies such as mesenchymal stem cell therapy and fecal microbiota transplantation. Future efforts should be guided by this paradigm shift, prioritizing the resolution of specific translational challenges inherent to these emerging treatments, fostering the multidisciplinary collaboration essential in clinical practice, and advancing toward more predictive, preventive, and personalized management strategies for RE. These findings provide valuable insights and guidance for future clinical research and innovation in this field.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.