ArticleJornal vascular brasileiro2026
Acute arterial occlusion following inadvertent infusion of ferric hydroxide sacarate (Noripurum®) into the radial artery: case report.
Article in Jornal vascular brasileiro, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Iron overload, whether acute or chronic, has been implicated in the pathogenesis of ischemic cardiovascular diseases. However, its effects on peripheral vascular function and thrombotic responses to endothelial injury remain incompletely elucidated. We present a case of inadvertent intra-arterial infusion of ferric hydroxide saccharate (Noripurum®), resulting in severe acute arterial occlusion, most likely secondary to diffuse endothelial injury. Despite prompt surgical intervention and adjunctive pharmacological therapy, the clinical outcome was unfavorable. Given the lack of similar reports in major scientific databases and the involvement of complex, yet poorly characterized, interactions between iron overload and endothelial dysfunction, this case contributes valuable insights into the vascular implications of parenteral iron administration.
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