ArticleBioinformation2025
Evaluation of antioxidant enzyme activity among Indian patients with type 2 diabetes mellitus.
Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oxidative stress is a key factor in the pathogenesis of Type 2 Diabetes Mellitus (T2DM), and the role of antioxidant enzymes in managing this stress remains an important area of research. Therefore, it is of interest to investigate the activity of antioxidant enzymes (SOD, CAT and GPx) in patients with Type 2 Diabetes Mellitus (T2DM) to understand the relationship between glycemic control and oxidative stress. We found significantly lower enzyme activity in individuals with poor glycemic control (HbA1c ≥ 7%) compared to those with better control (HbA1c < 7%). Negative correlations were observed between antioxidant enzyme levels and clinical variables such as HbA1c and fasting blood glucose. Our findings suggest that antioxidant enzyme activity may play a crucial role in managing oxidative stress in T2DM. Further studies should explore the potential of antioxidant-based therapies. The advancement to knowledge in this study is the identification of reduced antioxidant enzyme activity in patients with poor glycemic control, highlighting its potential role in managing oxidative stress in Type 2 Diabetes Mellitus.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.