ArticleJournal of oral microbiology2026
Healthy lifestyle and periodontitis: a multi-omics cross-sectional study in a Chinese cohort.
Article in Journal of oral microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The oral‒gut axis in periodontal disease: a systematic review of the associated human evidence of its mechanisms and implications for patient care.Journal of oral microbiology · 2026Review
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aimed to examine the association between an overall healthy lifestyle and periodontitis in a Chinese population. We further sought to explore the features of lifestyle-related oral microbiota, gut microbiota and plasma metabolome in relation to periodontitis. Design: This cross-sectional study included 2,182 Chinese adults from the Lanxi cohort. The overall lifestyle assessment included waist circumference, smoking status, drinking status, physical activity and diet. Periodontitis was diagnosed in accordance with the criteria of the American Academy of Periodontology. 16S rRNA sequencing was used to analyze the oral and gut microbiota, while an untargeted metabolome was employed for plasma metabolite profiling. Results: Participants with a healthy lifestyle had a lower prevalence of periodontitis than those with an unhealthy lifestyle (adjusted OR = 0.75, 95% CI: 0.59-0.96). Significant differences were observed in oral microbiota, gut microbiota and plasma metabolome between participants in the healthy and unhealthy lifestyle groups. Further analysis identified 12 lifestyle-related oral microbial genera, 12 gut microbial genera and 10 plasma metabolites, suggesting potential biological links between lifestyle and periodontal health. Conclusions: These findings suggest a potential association between a healthy lifestyle and periodontitis, with the oral and gut microbiota and plasma metabolome potentially involved.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.