ArticleACS omega2026
Dual-Loaded Galangal Extract and Lemongrass Oil Biobased Self-Emulsifying System for Denture-Cleansing Applications.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
5 authors.
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Abstract
Denture stomatitis, an inflammation involving the formation of plaque material on the denture surfaces, presents a great deal of difficulty for denture wearers. Although denture cleansers are widely used to prevent this condition, commercial formulations containing inorganic ingredients can cause adverse health effects, promote microbial proliferation, and alter denture color. To address these limitations, we developed, for the first time, a dual-loaded galangal extract (GE) and lemongrass oil (LGO) solid self-emulsifying drug delivery system (solid-SEDDS-GL) as a novel natural-based denture cleanser powder. Gas chromatography-mass spectrometry (GC-MS) analysis revealed that the major bioactive compounds in GE and LGO were 1'-acetoxychavicol acetate (ACA) and citral (neral and geranial), respectively. Solid-SEDDS-GL formulations were developed and characterized for their physicochemical properties, antifungal activity against
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