Evidence map›Paper›PMID 41908439›Full record

ReviewACS omega2026

The SOS Response: A Double-Edged Sword between the Persister and Resister Formation.

Kushala Ravikumar, Krishna Kurthkoti

Abstract readReview
In one paragraph

Review in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kushala RavikumarLaboratory of Molecular Microbiology, School of Bioscience, Chanakya University Bengaluru 562165, India.
Krishna KurthkotiLaboratory of Molecular Microbiology, School of Bioscience, Chanakya University Bengaluru 562165, India.ORCID https://orcid.org/0000-0002-6523-1091

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial agents have revolutionized the treatment of infectious diseases; however, their widespread and extensive use has accelerated the emergence of antimicrobial resistance (AMR). While resistance driven by mutation and gene transfer poses a major threat, the transiently dormant subpopulation, called persisters, poses an equally significant challenge. The bacterial SOS response, triggered by extensive DNA damage, promotes resistance by inducing mutations in the target protein, activating drug efflux systems and horizontally transferring genetic material. Furthermore, SOS has been implicated in controlling toxin-antitoxin modules, as observed in the

Identifiers

PMID41908439
PMCPMC13019380

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.