Evidence map›Paper›PMID 41909644›Full record

ArticleRadiology advances2026

Self-reported comprehension of large language model-generated summaries of lung cancer screening reports: a vignette survey.

Juan A Serna, Yannan Yu, Parris Diaz, Koharu Sakiyama, Meng Ye, Alison Rustagi, Jae Ho Sohn

Abstract read
In one paragraph

Article in Radiology advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Juan A SernaDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA 94143, United States.
Yannan YuDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA 94143, United States.
Parris DiazDepartment of Medicine, California Pacific Medical Center, San Francisco, CA 94109, United States.
Koharu SakiyamaDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA 94143, United States.
Meng YeCenter for Vision Technologies, SRI International, Menlo Park, CA 94025, United States.
Alison RustagiCenter for Data to Discovery and Delivery Innovation (3DI), San Francisco VA Health Care System, San Francisco, CA 94121, United States.
Jae Ho SohnDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA 94143, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients access radiology reports without delay, which can cause anxiety and misunderstanding. While large language models (LLMs) can generate patient-friendly summaries (PS) to mitigate this, their potential to address literacy-based disparities remains unquantified. Purpose: To measure the effect of LLM-generated PS on the objective comprehension and subjective experiences of individuals reading lung cancer screening computed tomography reports, and to determine the differential impact with respect to self-rated English and health literacy. Materials and Methods: This cross-sectional survey (July 24-28, 2025) used a within-subjects design. Participants from the online research platform Results: A total of 1815 participants (mean age, 46 years ± 16 [SD]; 919 women) who completed the survey were evaluated. The addition of a PS improved objective comprehension ( Conclusion: LLM-generated PS of lung cancer screening reports increase comprehension and reduce anxiety, most notably among individuals with lower self-rated English and health literacy. If validated in a patient population, they represent a potential tool to improve communication.

Indexed as

CThealth equitylarge language modellung cancer screeningLung-RADSpatient-friendly summarysurvey

Identifiers

PMID41909644
PMCPMC13020909

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.