Evidence map›Paper›PMID 41909896›Full record

ArticleGut microbes reports2025

Sarcopenia-related gut microbiota in the elderly: Insights from the longevity region of Kyotango and its nutritional associations.

Takeshi Yasuda, Tomohisa Takagi, Yuji Naito, Ryo Inoue, Katsura Mizushima, Kouhei Asaeda, Hikaru Hashimoto, Hiroaki Kitae, Kazuhiko Uchiyama, Norihiro Ouchi and 4 more

Abstract read
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In one paragraph

Article in Gut microbes reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Takeshi YasudaDepartment of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.ORCID https://orcid.org/0000-0002-7387-7511
Tomohisa TakagiDepartment of Molecular Gastroenterology and Hepatology/Department for Medical Innovation and Translational Medical Science, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.ORCID https://orcid.org/0000-0002-6119-4828
Yuji NaitoDepartment of Human Immunology and Nutrition Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.ORCID https://orcid.org/0000-0001-5443-788X
Ryo InoueDepartment of Applied Biological Sciences, Faculty of Agriculture, Setsunan University, Osaka, Japan.
Katsura MizushimaDepartment of Human Immunology and Nutrition Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Kouhei AsaedaDepartment of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Hikaru HashimotoDepartment of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Hiroaki KitaeDepartment of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Kazuhiko UchiyamaDepartment of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Norihiro OuchiDepartment of Internal Medicine, Kyotango Municipal Yasaka Hospital, Kyoto, Japan.
Atsuo AdachiDepartment of Internal Medicine, Kyotango Municipal Yasaka Hospital, Kyoto, Japan.
Tadaaki KamitaniDepartment of Internal Medicine, Kyotango Municipal Yasaka Hospital, Kyoto, Japan.
Satoaki MatobaDepartment of Cardiovascular Medicine/Department of Longevity and Regional Epidemiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Yoshito ItohDepartment of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sarcopenia is influenced by the gut microbiota and dietary habits; however, the underlying mechanisms remain elusive. This study investigated the gut microbiota composition of elderly individuals in a healthy longevity region and examined its association with sarcopenia and dietary habits. Fecal metagenomic analysis was used to identify gut microbiota taxonomy. Sarcopenia was diagnosed on the basis of grip strength, gait speed, and muscle volume. Japanese dietary habits were assessed using a brief-type self-administered diet history questionnaire. A total of 318 elderly individuals from Kyotango were recruited, 5.7% of whom were diagnosed with sarcopenia. Individuals with sarcopenia exhibited a lower abundance of a genus belonging to the family

Indexed as

butyrate-producing bacteriagut microbiotaJapanese dietary cultureJapanese diet indexSarcopenia

Identifiers

PMID41909896
PMCPMC12940105

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.