Evidence map›Paper›PMID 41910031›Full record

ReviewJournal of geriatric psychiatry and neurology2026

The Role of Posttraumatic Stress Disorder as a Risk Factor for Dementia: A Meta-Analysis.

Demi C D Havermans, Chris M Hoeboer, Theresia M Farrell, Colton S Rippey, Cristina N Pinheiro, Sjacko Sobczak, Miranda Olff, Stephanie Henderson, Kay Deckers, Karen A Lawrence

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of geriatric psychiatry and neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Demi C D HavermansDepartment of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands.ORCID 0000-0001-8815-6541
Chris M HoeboerDepartment of Psychiatry, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands.
Theresia M FarrellCollege of Social Work, University of Kentucky, Lexington, KY, USA.ORCID 0000-0002-8252-1576
Colton S RippeyDepartment of Psychology, University of Kentucky, Lexington, KY, USA.
Cristina N PinheiroDepartment of Psychology, University of Kentucky, Lexington, KY, USA.
Sjacko SobczakDepartment of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands.
Miranda OlffDepartment of Psychiatry, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands.
Stephanie HendersonMedical Center Library, University of Kentucky, Lexington, KY, USA.
Kay DeckersAlzheimer Centre Limburg, Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute (MHeNs), Maastricht University, Maastricht, The Netherlands.
Karen A LawrenceCollege of Social Work, University of Kentucky, Lexington, KY, USA.

Funding

Cognitive Aging Trajectories in Survivors of TraumaK01AG070279 · NIA · UNIVERSITY OF KENTUCKY · PI KAREN Ann LAWRENCE · 2023 to 2026
$501k
NIA NIH HHS K01 AG070279NIA NIH HHS L30 AG088356
6 · The paper itself

Abstract

BackgroundDementia is a growing global health concern, particularly among individuals with Posttraumatic Stress Disorder (PTSD), which may be a potential risk factor. However, the effects of moderating factors remain unclear.PurposeThis study aims to assess the relationship between PTSD and dementia risk, including potential moderators. Research designA systematic literature review and meta-analysis were conducted in PubMed, CINAHL, PsycINFO, The Cochrane Library, and Scopus.Data analysisRandom-effects meta-analyses were performed separately for unadjusted risk ratios (RRs) calculated from raw data and adjusted hazard ratios (HRs) reported from survival analyses. Subgroup and moderator analyses examined effects of population type, study quality, demographics, health and lifestyle factors on the PTSD-dementia association.Study sampleEighteen studies were included after screening 30,203 abstracts and 621 full-text articles.ResultsPTSD was associated with a 43% (unadjusted pooled RR = 1.43, 95% CI:1.09-1.89, I

Indexed as

dementiaolder adultsPTSDrisk factors

Identifiers

PMID41910031
PMCPMC13623202

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.