Evidence map›Paper›PMID 41910274›Full record

ReviewJournal of virology2026

From CRISPR functional genomics to synthetic interventions: engineering antiviral strategies.

Wenjie Qiao

Abstract readReview
In one paragraph

Review in Journal of virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Wenjie QiaoInstitute of Infectious Diseases, Shenzhen Bay Laboratory, Shenzhen, China.ORCID 0009-0006-0014-9499

Funding

Shenzhen Bay Laboratory C1032633001
6 · The paper itself

Abstract

Virus-host interactions govern infection outcomes and viral evolution, but host determinants that enable or restrict viral replication have been difficult to map comprehensively and in the right cellular contexts. Pooled CRISPR perturbation screens now provide scalable, mechanistic entry points into host dependency and restriction landscapes across diverse viruses. Recent extensions, including single-cell readouts, imaging and spatial phenotyping, organoid models, and

Indexed as

Antiviral AgentsClustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsGenomicsSynthetic BiologyVirus DiseasesAnimalsHost-Pathogen InteractionsHumansVirusesVirus ReplicationAntiviral Agentsantiviral strategiesCRISPR screeningfunctional genomicssynthetic biologyvirus-host interactions

Identifiers

PMID41910274
PMCPMC13098268

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.