Evidence map›Paper›PMID 41910918›Full record

ArticleDiscover nano2026

Biosynthesis of selenium nanoparticles by Aloe vera leaf extract and its biomedical applications.

Aya M El-Ebidy, Amr M Mowafy, Heba M M Abdel-Aziz

Erratum issuedAbstract read
In one paragraph

Article in Discover nano, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Aya M El-EbidyBotany Department, Faculty of Science, Mansoura University, Mansoura, Egypt.
Amr M MowafyBotany Department, Faculty of Science, Mansoura University, Mansoura, Egypt.
Heba M M Abdel-AzizBotany Department, Faculty of Science, Mansoura University, Mansoura, Egypt. hebammabdelaziz@mans.edu.eg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAloe vera has been cultivated mainly for medicinal purposes, with over 75 biologically active compounds in its gel. Selenium nanoparticles (SeNPs) are novel selenium sources characterized by great biocompatibility, low toxicity, stability, selectivity, and extensive uses. This study emphasizes the significant role of phytofabricated SeNPs in several biomedical applications. METHODS &

resultsSeNPs were synthesized utilizing Aloe vera leaf extract. The biosynthesized SeNPs were characterized using UV-Vis, EDX, XRD, zeta potential, FTIR, and TEM analyses. The antioxidant, antibacterial, anti-inflammatory, and anticancer effects, along with the impact on antioxidant enzymes of biosynthesized SeNPs, were evaluated. The biomedical functions of SeNPs were concentration-dependent, showing antibacterial activity against both Gram-positive bacteria (Bacillus cereus, Staphylococcus aureus, and Bacillus subtilis) and Gram-negative (Escherichia coli, Salmonella typhimurium, and Klebsiella pneumonia). Additionally, SeNPs exhibited antioxidant activity, with DPPH scavenging from 77.39 ± 0.895% at 120 µg mL

conclusionsThe Bio-fabricated SeNPs exhibited nontoxicity and eco-friendliness, demonstrating notable antimicrobial efficacy, particularly against S. aureus, K. pneumonia, and B. subtilis. They also possess high DPPH scavenging capabilities, anti-inflammatory properties, and exhibit superior anticancer activity on the Caco2 cancerous cell line compared to the MCF7 cell line, while retaining WI38 normal cells, underscoring their potential in medical applications.

Indexed as

Aloe veraAnticancerAnti-inflammatoryCaco2 cell linesDPPH scavengingSelenium nanoparticles

Identifiers

PMID41910918
PMCPMC13036000

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.