Evidence map›Paper›PMID 41912628›Full record

ArticleScientific reports2026

Prognostic impact of acute kidney injury on one-year survival in patients undergoing high-risk PCI with Impella support.

J Sacha, F J Woitek, A Pietrasik, A Laupp, A Gąsecka, A Conrad, T Pawłowski, D Obradovic, M Grygier, S Haussig and 44 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

54 authors.

J SachaDepartment of Cardiology, University Hospital in Opole, University of Opole, Al. Witosa 26, 45-402, Opole, Poland. sacha@op.pl.
F J WoitekDepartment for Internal Medicine and Cardiology, Heart Centre Dresden, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
A PietrasikDepartment of Cardiology, Medical University of Warsaw, Warsaw, Poland.
A LauppDepartment for Internal Medicine and Cardiology, Heart Centre Dresden, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
A GąseckaDepartment of Cardiology, Medical University of Warsaw, Warsaw, Poland.
A ConradDepartment for Internal Medicine and Cardiology, Heart Centre Dresden, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
T PawłowskiDepartment of Cardiology, National Medical Institute of the Internal Affairs and Administration Ministry, Warsaw, Poland.
D ObradovicDepartment for Internal Medicine and Cardiology, Heart Centre Dresden, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
M Grygier1st Department of Cardiology, Poznan University of Medical Sciences, Poznan, Poland.
S HaussigDepartment for Internal Medicine and Cardiology, Heart Centre Dresden, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
G Bielawski2nd Department of Cardiology, Jan Biziel University Hospital No. 2, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Torun, Poland.
J MierkeDepartment for Internal Medicine and Cardiology, Heart Centre Dresden, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
W Balak2nd Department of Cardiology, Jan Biziel University Hospital No. 2, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Torun, Poland.
S JellinghausDepartment for Internal Medicine and Cardiology, Heart Centre Dresden, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
A SukiennikDepartment of Cardiology and Internal Diseases, University Hospital No. 1, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Torun, Poland.
P BurzyńskaDepartment of Cardiology and Internal Diseases, University Hospital No. 1, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Torun, Poland.
A WitkowskiDepartment of Interventional Cardiology and Angiology, National Institute of Cardiology, Warsaw, Poland.
M WarniełłoOddział Anestezjologii i Intensywnej Terapii, Uniwersyteckie Centrum Kliniczne im. Prof. K. Gibińskiego, Śląski Uniwersytet Medyczny, Katowice, Poland.
Ł RzeszutkoII Department of Cardiology, Collegium Medicum, Jagiellonian University, Kraków, Poland.
S BartuśII Department of Cardiology, Collegium Medicum, Jagiellonian University, Kraków, Poland.
A PawlikII Department of Cardiology, Collegium Medicum, Jagiellonian University, Kraków, Poland.
M KaczyńskiDepartment of Cardiology, National Medical Institute of the Internal Affairs and Administration Ministry, Warsaw, Poland.
R GilDepartment of Cardiology, National Medical Institute of the Internal Affairs and Administration Ministry, Warsaw, Poland.
W KuliczkowskiInstitute for Heart Diseases, Wroclaw Medical University, Wroclaw, Poland.
K ReczuchInstitute for Heart Diseases, Wroclaw Medical University, Wroclaw, Poland.
M ProtasiewiczDepartment of Non-Procedural Clinical Sciences, Wroclaw University of Science and Technology, Faculty of Medicine, Wroclaw, Poland.
P KleczyńskiDepartment of Interventional Cardiology, Institute of Cardiology, Jagiellonian University Medical College, John Paul II Hospital, Kraków, Poland.
P WańczuraCollege of Medical Sciences, University of Rzeszow, Rzeszów, Poland.
S GurbaCollege of Medical Sciences, University of Rzeszow, Rzeszów, Poland.
A KochanowskaDepartment of Cardiology, Medical University of Warsaw, Warsaw, Poland.
M ŁomiakDepartment of Cardiology, Medical University of Warsaw, Warsaw, Poland.
W Skorupski1st Department of Cardiology, Poznan University of Medical Sciences, Poznan, Poland.
M ZarębińskiIndependent Public Specialist Western Hospital John Paul II, Grodzisk Mazowiecki, Poland.
P PawluczukIndependent Public Specialist Western Hospital John Paul II, Grodzisk Mazowiecki, Poland.
S WłodarczakFaculty of Medicine, Wroclaw University of Science and Technology, Wroclaw, Poland.
A WłodarczakFaculty of Medicine, Wroclaw University of Science and Technology, Wroclaw, Poland.
K ŚciborskiCenter for Heart Diseases, Military Hospital in Wroclaw, Wrocław, Poland.
A TelichowskiCenter for Heart Diseases, Military Hospital in Wroclaw, Wrocław, Poland.
M PlucińskiDepartment of Interventional Cardiology and Cardiac Surgery, Collegium Medicum, University of Zielona Gora, Zielona Góra, Poland.
J HiczkiewiczDepartment of Interventional Cardiology and Cardiac Surgery, Collegium Medicum, University of Zielona Gora, Zielona Góra, Poland.
K Konsek3rd Department of Cardiology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Katowice, Poland.
M Hawranek3rd Department of Cardiology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Katowice, Poland.
M Gąsior3rd Department of Cardiology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Katowice, Poland.
J Peruga1st Department of Cardiology, Bieganski Hospital, Medical University, Łódź, Poland.
M Fiutowski1st Department of Cardiology, Bieganski Hospital, Medical University, Łódź, Poland.
R RomanekDepartment of Cardiology and Cardiac Surgery, 10Th Military Hospital and Polyclinic, Bydgoszcz, Poland.
P Kasprzyk1st Department of Cardiology, Medical University of Gdansk, Gdańsk, Poland.
D Ciećwierz1st Department of Cardiology, Medical University of Gdansk, Gdańsk, Poland.
A OchałaDepartment of Cardiology and Structural Heart Diseases, Medical University of Silesia, Katowice, Poland.
W WojakowskiDepartment of Cardiology and Structural Heart Diseases, Medical University of Silesia, Katowice, Poland.
J LegutkoDepartment of Interventional Cardiology, Institute of Cardiology, Jagiellonian University Medical College, John Paul II Hospital, Kraków, Poland.
A LinkeDepartment for Internal Medicine and Cardiology, Heart Centre Dresden, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
J KochmanDepartment of Cardiology, Medical University of Warsaw, Warsaw, Poland.
N MangnerDepartment for Internal Medicine and Cardiology, Heart Centre Dresden, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This multicenter study evaluated the prognostic impact of acute kidney injury (AKI) on one-year survival in patients undergoing Impella-supported high-risk percutaneous coronary intervention (hrPCI), and whether Impella use offers renal protection. A total of 470 patients from two independent cohorts were analyzed: the IMPELLA-PL group (n = 249, derivation cohort) and the Dresden group (n = 221, validation cohort). Patients with cardiogenic shock or chronic dialysis were not included. AKI-defined as a ≥ 0.5 mg/dL increase in serum creatinine within 72 h-occurred in 13.3% and 14.9% of patients, respectively, which was significantly lower than the predicted 26.1% risk based on the Mehran Risk Score. AKI was an independent predictor of one-year mortality in both the derivation (HR: 2.75; 95% CI: 1.11-6.82) and validation (HR: 2.16; 95% CI: 1.12-4.10) cohorts. Upfront Impella implantation and higher baseline glomerular filtration rate were independently associated with a reduced risk of AKI in both cohorts. The adverse effect of AKI on long-term survival was significant in males, but not in females. These findings indicate that although AKI remains a strong prognostic marker following hrPCI, early Impella support may mitigate this risk. The results also suggest potential sex-related differences in susceptibility to renal complications following complex coronary interventions.

Indexed as

Acute Kidney InjuryHeart-Assist DevicesPercutaneous Coronary InterventionAgedCreatinineFemaleGlomerular Filtration RateHumansMaleMiddle AgedPrognosisRisk FactorsCreatinineComplex PCIContrast induced nephropathyMechanical circulatory supportMicroaxial pumpPercutaneous coronary intervention

Identifiers

PMID41912628
PMCPMC13039172

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.