Evidence map›Paper›PMID 41912702›Full record

ReviewJournal of perinatology : official journal of the California Perinatal Association2026

Factors influencing SARS-CoV-2 placental antibody transfer and neonatal transmission. A prospective, cohort study and review of available literature.

Júlia Candel-Pau, Sílvia Maya-Enero, Jordi García-García, Beatriz Valle-Del Barrio, José Muñoz-Molinero, Maria Ángeles López-Vílchez

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Júlia Candel-PauDepartment of Neonatology, Service of Pediatrics, Hospital del Mar Barcelona, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain. jcandelpau@hmar.cat.ORCID http://orcid.org/0000-0002-5646-8302
Sílvia Maya-EneroDepartment of Neonatology, Service of Pediatrics, Hospital del Mar Barcelona, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain.ORCID http://orcid.org/0000-0002-0102-611X
Jordi García-GarcíaDepartment of Neonatology, Service of Pediatrics, Hospital del Mar Barcelona, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain.
Beatriz Valle-Del BarrioDepartment of Neonatology, Service of Pediatrics, Hospital del Mar Barcelona, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain.ORCID http://orcid.org/0000-0002-6285-383X
José Muñoz-MolineroLaboratori de Referència de Catalunya, c/ Selva 10, Edif. INBLAU, Parque de Negocios Mas Blau, El Prat de Llobregat, Barcelona, Catalonia, Spain.
Maria Ángeles López-VílchezDepartment of Neonatology, Service of Pediatrics, Hospital del Mar Barcelona, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain.ORCID http://orcid.org/0000-0001-8865-9405

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe SARS-CoV-2 serologic status, associated factors, and neonatal transmission following gestational COVID-19. STUDY

designProspective cohort study including neonates born to mothers with gestational COVID-19 at Hospital del Mar (Barcelona) between March 2020 and May 2022.

resultsA total of 263 infants and 261 mothers were included. High seropositivity was observed in infected mothers (88.9%) and their newborns (82.8%), particularly following early gestational and mild-to-moderate infections and among vaccinated mothers. Higher placental antibody transfer ratios were observed in earlier maternal infections. However, a longer infection-to-delivery interval increased transfer ratios only for anti-nucleocapsid antibodies. Neonatal antibodies persisted for at least six months. Only 6.1% of neonates born to mothers with active infection tested positive, with no evidence of congenital transmission.

conclusionsSARS-CoV-2 antibody placental transfer is frequent and efficient, conferring passive immunity during the first six months of life. Neonatal infection rate was low and attributable to horizontal transmission.

Indexed as

Antibodies, ViralCOVID-19Immunity, Maternally-AcquiredInfectious Disease Transmission, VerticalPlacentaPregnancy Complications, InfectiousSARS-CoV-2AdultFemaleHumansInfant, NewbornMalePregnancyProspective StudiesAntibodies, Viral

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.