Evidence map›Paper›PMID 41913081›Full record

ArticleJournal of human nutrition and dietetics : the official journal of the British Dietetic Association2026

Effects of Undernutrition and Obesity on Functional and Nutritional Outcomes After Ischaemic Stroke: A Hospital-Based Study.

Daniela Figueiredo Corrêa Pereira, Karen Barros Parron Fernandes, Andreo Fernando Aguiar, Sergio Marques Borghi, Kamila Grandolfi, Juliano Casonatto

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Article in Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Daniela Figueiredo Corrêa PereiraResearch Group in Physiology and Physical Activity, University Pitágoras UNOPAR Anhanguera, Londrina, Paraná, Brazil.ORCID https://orcid.org/0009-0000-6705-5127
Karen Barros Parron FernandesDepartment of Medicine, Pontifical Catholic University, Londrina, Paraná, Brazil.ORCID https://orcid.org/0000-0002-1276-4900
Andreo Fernando AguiarResearch Laboratory in Muscular System and Physical Exercise, University Pitágoras UNOPAR Anhanguera, Londrina, Paraná, Brazil.ORCID https://orcid.org/0000-0003-3337-2444
Sergio Marques BorghiCenter for Research in Biological and Health Sciences, University Pitágoras UNOPAR Anhanguera, Londrina, Paraná, Brazil.ORCID https://orcid.org/0000-0002-6978-7505
Kamila GrandolfiResearch Group in Physiology and Physical Activity, University Pitágoras UNOPAR Anhanguera, Londrina, Paraná, Brazil.ORCID https://orcid.org/0000-0002-8286-6072
Juliano CasonattoResearch Group in Physiology and Physical Activity, University Pitágoras UNOPAR Anhanguera, Londrina, Paraná, Brazil.ORCID https://orcid.org/0000-0001-5397-5694

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe impact of nutritional status on post-stroke outcomes remains controversial, particularly regarding the opposing effects of undernutrition and obesity on recovery. This study investigated how these nutritional conditions influence functional and nutritional outcomes among hospitalized ischaemic stroke survivors.

methodsA retrospective study analyzed 160 adults with radiologically confirmed ischaemic stroke admitted to a Brazilian tertiary hospital. Nutritional status was classified by WHO BMI criteria (undernutrition: BMI < 18.5 kg/m

resultsUndernutrition (n = 36) showed strong associations with disability (adjusted OR 6.64, 95% CI 2.19-20.14), symptomatic presentation (aOR 2.84, 1.16-6.94) and reduced food intake (aOR 5.69, 2.28-14.21). Obesity (n = 30) was independently linked to higher disability risk after adjustment (aOR 3.32, 1.02-10.80). Estimated marginal probabilities (vs. normal/overweight BMI reference group) revealed that undernourished patients had 47.7% disability risk (vs. 12.1% in nourished) and obese patients 39.2% (vs. 16.2% in non-obese).

conclusionsUndernutrition and obesity independently predict worse functional recovery and nutritional outcomes post-stroke, with undernutrition additionally compromising food intake. The so-called obesity paradox was not sustained after mutual adjustment. Findings underscore the importance of: (1) early nutritional screening, (2) intensified support for undernourished patients and (3) tailored rehabilitation strategies for obese individuals.

Indexed as

Ischemic StrokeMalnutritionNutritional StatusObesityStrokeAgedAged, 80 and overBody Mass IndexBrazilFemaleHospitalizationHumansLength of StayLogistic ModelsMaleMiddle Ageddisabilitynutritional assessmentobesity paradoxstroke outcomesundernutrition

Identifiers

PMID41913081
PMCPMC13035919

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.