Evidence map›Paper›PMID 41913108›Full record

ArticleBMC anesthesiology2026

Quality management of comprehensive blood conservation strategies during cardiopulmonary bypass in pediatric cardiac surgery.

Wenting Wang, He Wang, Jia Liu, Yu Jin, Jinping Liu

Abstract read
In one paragraph

Article in BMC anesthesiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wenting WangDepartment of Anesthesiology, The Second Affiliated Hospital of Hainan Medical University, 570311, Haikou, China.
He WangDepartment of Cardiopulmonary Bypass, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 100037, Beijing, China.
Jia LiuDepartment of Cardiopulmonary Bypass, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 100037, Beijing, China.
Yu JinDepartment of Cardiopulmonary Bypass, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 100037, Beijing, China.
Jinping LiuDepartment of Cardiopulmonary Bypass, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 100037, Beijing, China. liujinping@fuwai.com.

Funding

Academic Enhancement Support Program of Hainan Medical University XSTS2025095the CAMS Innovation Fund for Medical Sciences(CIFMS) 2024-12M-C&T-B-045the Fundamental Research Funds for the Central Universities, Peking Union Medical College 3332025040the New Star Program of the South China Sea, Hainan Province NHXX-WJW-2025011
6 · The paper itself

Abstract

backgroundPediatric cardiac surgery with cardiopulmonary bypass (CPB) carries substantial transfusion requirements, exposing patients to increased risks of complications during hospital stay. This study evaluates the clinical impact of a quality-controlled, multimodal blood conservation strategy during CPB in pediatric cardiac surgery.

methodsWe collected the medical data of 9792 children (aged ≤ 14 years and weight > 10 kg) undergoing CPB cardiac surgery between September 2014 and December 2021. Since January 2016, the pediatric CPB center has implemented patient blood management. Subsequently, patients were divided into two groups: conventional management group (premanagement, n = 1762) and patient blood management group (postmanagement, n = 8030). Compare blood transfusion and outcomes. A 1:1 propensity score matching was performed.

results1760 matched patient pairs were obtained. Compared with the premanagement group, the postmanagement group demonstrated significant reduction in packed red blood cell (PRBC) transfusion rates (during hospital stay: 38.1% vs. 33.6%, p = 0.007; CPB: 18.2% vs. 11.1%, p < 0.001), lower plasma transfusion rates (20.7% vs. 16.6%, p = 0.002), furthermore, decreased CPB priming volume (29.2 vs. 29.1 mL/kg, p = 0.042), lower incidence of postoperative liver injury (15.7% vs. 10.5%, p < 0.001) and AKI (7.5% vs. 5.5%, p = 0.017).

conclusionsFollowing the postmanagement, comprehensive blood conservation strategies significantly reduce transfusion requirements and improve clinical outcomes for this vulnerable population, establishing an effective framework for blood resource utilization and safety during hospital stay.

Indexed as

Blood TransfusionCardiac Surgical ProceduresCardiopulmonary BypassAdolescentChildChild, PreschoolErythrocyte TransfusionFemaleHumansInfantLength of StayMalePostoperative ComplicationsRetrospective StudiesBlood conservationCardiopulmonary bypassPatient blood managementPediatric cardiac surgeryQuality managementTransfusion medicine

Identifiers

PMID41913108
PMCPMC13154674

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.