Evidence map›Paper›PMID 41913535›Full record

ArticleAlcohol, clinical & experimental research2026

The 10-year stability of three subscale scores of the Self-Report of the Effects of Alcohol measure and their relationship to changes in drinking quantities over the same period.

Marc A Schuckit, Tom L Smith, George Danko, Lee Anne Mendoza, Victor Hesselbrock, Samuel Kuperman, Fanghong Dong, Chella Kamarajan, Grace Chan, Yue Wang and 4 more

Abstract read
In one paragraph

Article in Alcohol, clinical & experimental research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Marc A SchuckitDepartment of Psychiatry, University of California San Diego Medical School, San Diego, California, USA.
Tom L SmithDepartment of Psychiatry, University of California San Diego Medical School, San Diego, California, USA.
George DankoDepartment of Psychiatry, University of California San Diego Medical School, San Diego, California, USA.
Lee Anne MendozaDepartment of Psychiatry, University of California San Diego Medical School, San Diego, California, USA.
Victor HesselbrockDepartment of Psychiatry, University of Connecticut School of Medicine, Farmington, Connecticut, USA.ORCID https://orcid.org/0000-0002-0495-8641
Samuel KupermanDepartment of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.
Fanghong DongDepartment of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID https://orcid.org/0000-0001-6696-5196
Chella KamarajanDepartment of Psychiatry, State University of New York Downstate Health Sciences University, Brooklyn, New York, USA.
Grace ChanDepartment of Psychiatry, University of Connecticut School of Medicine, Farmington, Connecticut, USA.ORCID https://orcid.org/0000-0002-1257-6889
Yue WangDepartment of Psychiatry, Indiana University, Indianapolis, Indiana, USA.
Gayathri PandeyDepartment of Psychiatry, State University of New York Downstate Health Sciences University, Brooklyn, New York, USA.
Alex P MillerDepartment of Psychiatry, Indiana University, Indianapolis, Indiana, USA.ORCID https://orcid.org/0000-0001-9163-8947
Martin H PlaweckiDepartment of Psychiatry, Indiana University, Indianapolis, Indiana, USA.
Andrey P AnokhinDepartment of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.

Funding

Subject CollectionU10AA008401 · NIAAA · SUNY DOWNSTATE MEDICAL CENTER · PI Sarah Hartz · 1989 to 2026
$162.7M
NIAAA NIH HHS U10 AA008401
6 · The paper itself

Abstract

objectivesThe retrospective self-report of the effects of alcohol (SRE) questionnaire generates three scores reflecting drinking quantities required for effects: SRE-5 (first five times of drinking), SRE-3 (recent 3 months of drinking), and SRE-H (heaviest drinking). Data to date indicate that SRE-5 scores, potentially reflecting genetic effects, have high reliabilities across 9 months. Data presented here evaluated the consistencies of all three SRE scores obtained five times over a decade.

methodParticipants were 331 young adults (45% male) from the Collaborative Study on the Genetics of Alcoholism (COGA) Prospective Study of youth who completed the SRE and were evaluated at least five times using the Semi-Structured Assessment for the Genetics of Alcoholism interview. Analyses documented changes in SRE scores, changes in drinking quantities, and the relationship between these measures over time using repeated measures ANOVA and regression analyses.

resultsSRE-5 scores did not change significantly across evaluations despite significant changes in drinking quantities. SRE-3 and SRE-H demonstrated significant changes over time that related to changes in drinking quantities during each period. Participants with low levels of response (low LRs) to alcohol, based on a median split of SRE-5 at Time 1, were likely to remain low LR throughout the decade.

conclusionsThis is the first report on the longer-term consistency of all three SRE scores during a decade of life in which a person's heaviest drinking and AUD development are likely to occur. Results indicate that retrospective SRE-5 scores, potentially reflecting genetic predispositions to AUD, do not change over a decade despite changes in drinking patterns.

Indexed as

Alcohol DrinkingSelf ReportAdolescentAlcoholismFemaleHumansMaleProspective StudiesRetrospective StudiesSurveys and QuestionnairesYoung Adultalcoholismalcohol responseCOGAprospectiveSRE

Identifiers

PMID41913535
PMCPMC13036369

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.