Evidence map›Paper›PMID 41913929›Full record

ArticlePeerJ2026

The relationship between controlling nutritional status (CONUT) and cerebrovascular stenosis: a retrospective study with implications for ischemic stroke prevention.

Ning Wang, Kun Guo, Bo Zhu, Yuanzhi Zhang, Xiaotao Jia, Zhiqin Liu, Zhengli Di, Naibing Gu, Ting Li

Abstract read
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Article in PeerJ, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Ning Wang *The Third Affiliated Hospital of Xi'an Medical University, Xi'an, Shaanxi, China.
Kun Guo *Department of Neurology, Tongchuan Mining Bureau Central Hospital, Tongchuan, Shaanxi Province, China.
Bo ZhuDepartment of Neurology, Nuclear Industry 215 Hospital of Shaanxi Province/215 Hospital of Shaanxi Province, Xian Yan, Shaanxi, China.
Yuanzhi ZhangDepartment of General Medicine, Xi'an Central Hospital, Xi'an, Shaanxi Province, China.
Xiaotao JiaDepartment of Neurology, Xi'an Central Hospital, Xi'an, Shaanxi Province, China.
Zhiqin LiuDepartment of Neurology, Xi'an Central Hospital, Xi'an, Shaanxi Province, China.
Zhengli DiDepartment of Neurology, Xi'an Central Hospital, Xi'an, Shaanxi Province, China.
Naibing GuDepartment of Neurology, Xi'an Central Hospital, Xi'an, Shaanxi Province, China.
Ting LiDepartment of Neurology, Tongchuan Mining Bureau Central Hospital, Tongchuan, Shaanxi Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Ischemic stroke, a major global health concern, has high incidence, mortality, and disability rates. Cerebrovascular stenosis, a significant risk factor, is often assessed using digital subtraction angiography (DSA), which is invasive and costly. The Controlling Nutritional Status (CONUT) score, originally designed to assess malnutrition, has potential value in predicting vascular stenosis and stroke prognosis. Methods: This study analyzed 1,057 inpatients from Xi'an Central Hospital and Tongchuan Mining Bureau Central Hospital who underwent DSA for cerebrovascular stenosis from January 2016 to June 2024, comparing 674 patients with stenosis to 383 without. The CONUT score, calculated from serum albumin, lymphocyte count, and total cholesterol, was evaluated for its association with stenosis severity. Statistical analyses included t-tests, Mann-Whitney U tests, chi-square tests, Spearman correlation, stepwise regression, and ROC curve analysis, and age/comorbidity subgroup analyses. Results: CONUT scores were significantly higher in stenosis Conclusion: The CONUT score is an independent predictor of cerebrovascular stenosis severity, with particular utility in elderly populations. It provides a practical, non-invasive tool for preliminary stenosis screening, potentially reducing unnecessary DSA referrals.

Indexed as

Ischemic StrokeNutritional StatusAgedAged, 80 and overAngiography, Digital SubtractionChinaConstriction, PathologicFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsROC CurveSeverity of Illness IndexCerebral vascular stenosisCONUT scoreCorrelation analysisIschemic stroke

Identifiers

PMID41913929
PMCPMC13033285

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.