Evidence map›Paper›PMID 41914528›Full record

ArticleAllergy, asthma & immunology research2026

Impact of Health Insurance Type on Access to Biologics and Systemic Corticosteroid Exposure in Patients With Severe Asthma: A Real-World Study From the Korean Severe Asthma Registry (KoSAR).

Kyoung-Hee Sohn, Sun-Kyung Lee, Hwa Young Lee, So Ri Kim, Seung Eun Lee, Joo-Hee Kim, Woo-Jung Song, Sang-Heon Kim, Korean Severe Asthma Registry (KoSAR) Investigators

Abstract read
In one paragraph

Article in Allergy, asthma & immunology research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kyoung-Hee SohnDivision of Pulmonary and Allergy, Department of Internal Medicine, Kyung Hee University Hospital, Kyung Hee University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-8407-8080
Sun-Kyung LeeDivision of Pulmonary Medicine and Allergy, Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-0033-1339
Hwa Young LeeDivision of Allergy, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0002-1582-2256
So Ri KimDivision of Respiratory Medicine and Allergy, Department of Internal Medicine, Jeonbuk National University Medical School, Jeonju, Korea.ORCID https://orcid.org/0000-0002-6074-9158
Seung Eun LeeDepartment of Internal Medicine, Pusan National University Yangsan Hospital, School of Medicine, Pusan National University, Yangsan, Korea.ORCID https://orcid.org/0000-0002-4266-7722
Joo-Hee KimDepartment of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University Medical School, Anyang, Korea.ORCID https://orcid.org/0000-0002-1572-5149
Woo-Jung SongDepartment of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-4630-9922
Sang-Heon KimDivision of Pulmonary Medicine and Allergy, Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea. sangheonkim@hanyang.ac.kr.ORCID https://orcid.org/0000-0001-8398-4444
Korean Severe Asthma Registry (KoSAR) Investigators

Funding

Korea National Institute of Health 2025-ER1201-01Kyung Hee University 20222250
6 · The paper itself

Abstract

purposeThe impact of socioeconomic status on asthma control has been widely investigated. However, evidence regarding the impact of health insurance type on biologic utilization and systemic corticosteroid (SCS) exposure among patients with severe asthma remains limited. This study aimed to evaluate the associations between health insurance type, biologic utilization, and SCS dose in South Korea.

methodsData from the Korean Severe Asthma Registry (KoSAR) between March 2022 and October 2023 were analyzed. Patients were categorized into 4 different groups based on their health insurance type: National Health Insurance (NHI) with private health insurance (PHI), NHI-only, and Medical Aid (MA) with PHI, and MA-only.

resultsAmong the 578 patients with severe asthma, 327 (56.6%) were classified as NHI+PHI, 192 (33.2%) as NHI-only, 22 (3.8%) as MA+PHI, and 37 (6.4%) as MA-only. Decline in lung function, asthma exacerbations, and impaired quality of life were significantly more prevalent in the MA+PHI and MA-only groups. Overall, 159 patients (27.5%) were identified as biologic users. The most frequently prescribed biologics were dupilumab (8.8%), reslizumab (8.5%), omalizumab (7.1%), followed by mepolizumab (2.3%). Biologic utilization varied significantly by insurance type, with rates of 30.9% in the NHI+PHI group, 27.1% in the NHI-only group, and only 8.1% in the MA-only group (

conclusionsOur study showed that differences in biologic and SCS use were associated with insurance type. These findings suggest that insurance coverage and out-of-pocket expenses are important factors influencing access to optimal care for severe asthma, emphasizing the need for policy interventions to promote health equity.

Indexed as

Asthmabenralizumabdupilumabinsurancemepolizumabmonoclonal antibodyomalizumabreslizumab

Identifiers

PMID41914528
PMCPMC13047438

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.