Evidence mapPaperPMID 41916913Full record

ReviewZhongguo fei ai za zhi = Chinese journal of lung cancer2026

[Appropriate Duration of First-line Immunotherapy for 
Advanced NSCLC and Predictive Factors].

Yue Yin, Xiaotong Guo, Jing Ai, Jibo Yue, Lili Deng

Abstract readReviewEnglish Abstract
In one paragraph

Review in Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yue YinDepartment of Medical Oncology, Second Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Xiaotong GuoDepartment of Medical Oncology, Second Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Jing AiDepartment of Medical Oncology, Second Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Jibo YueDepartment of Medical Oncology, Second Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Lili DengDepartment of Medical Oncology, Second Affiliated Hospital of Harbin Medical University, Harbin 150001, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

First-line immunotherapy for advanced non-small cell lung cancer (NSCLC) shows significant survival benefits in patients without driver mutations, but the optimal duration of treatment remains controversial. Some studies support limiting immunotherapy to 2 years, arguing that longer treatment does not bring additional survival benefits; while other studies believe that treatment should continue until disease progression to maximize survival benefits. This article systematically reviews the current research progress on the duration of immunotherapy and discusses the potential predictive value of biomarkers such as circulating tumor DNA (ctDNA), the best efficacy response, and programmed cell death ligand 1 (PD-L1) expression levels in individualized treatment decisions. More prospective studies, especially biomarker-driven trials, are still needed to clarify the optimal duration of treatment and establish an individualized treatment strategy based on multidimensional indicators.
.

Indexed as

Carcinoma, Non-Small-Cell LungImmunotherapyLung NeoplasmsB7-H1 AntigenBiomarkers, TumorHumansB7-H1 AntigenBiomarkers, TumorctDNAEfficacy responseImmunotherapyLung neoplasmsPD-L1Treatment duration

Identifiers

PMID41916913
PMCPMC13046445

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.