ReviewAdvances in experimental medicine and biology2026
Pharmacophores of Influenza Virus PA Endonuclease Inhibitors.
Review in Advances in experimental medicine and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
Funding
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Abstract
With the emergence of the novel coronavirus in 2020, influenza viruses have remained out of the spotlight for some time. However, influenza viral infections have been reported in recent years, indicating that this pathogen remains a major threat. Therefore, in addition to elucidating the molecular mechanisms underlying viral proliferation, new drugs are being actively developed. One of the most effective targets for anti-influenza drugs is the endonuclease activity of the PA subunit, a component of the viral RNA-dependent polymerase, for which a wide variety of compounds have been reported to date. In this review, we introduce 100 compounds that inhibit the activity of this enzyme and the viral proliferation efficiency, showing their potential to be used as novel anti-influenza drugs.
Indexed as
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41917409What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.