ArticleNature neuroscience2026
Neuropeptide Y co-opts neuronal ensembles for memory lability and stability.
Abstract read
In one paragraph
Article in Nature neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Impact of serotonin transporter deficiency on parvalbumin- and neuropeptide Y-producing neurons of the lateral and basolateral amygdalar nuclei.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors.
Yan-Jiao Wu *Department of Anesthesiology, Songjiang Research Institute, Shanghai Key Laboratory of Emotions and Affective Disorders (LEAD), Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xue Gu *Department of Anatomy and Physiology, Key Laboratory of Anesthesiology (Shanghai Jiao Tong University), Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yalei Kong *Department of Anesthesiology, Songjiang Research Institute, Shanghai Key Laboratory of Emotions and Affective Disorders (LEAD), Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID http://orcid.org/0009-0004-5109-3494
Shuo Yang *Department of Anesthesiology, Songjiang Research Institute, Shanghai Key Laboratory of Emotions and Affective Disorders (LEAD), Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Huan WangState Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Beijing, China.ORCID http://orcid.org/0000-0002-7472-0057
Miao XuDepartment of Rehabilitation Medicine, Huashan Hospital, Center for Clinical Neuro-AI, Institute for Translational Brain Research, State Key Laboratory of Brain Function and Disorders, and Ministry of Education Frontiers Center for Brain Science, Fudan University, Shanghai, China.
Qi WangDepartment of Anesthesiology, Songjiang Research Institute, Shanghai Key Laboratory of Emotions and Affective Disorders (LEAD), Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xin YiDepartment of Anatomy and Physiology, Key Laboratory of Anesthesiology (Shanghai Jiao Tong University), Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ze-Jie LinDepartment of Anesthesiology, Songjiang Research Institute, Shanghai Key Laboratory of Emotions and Affective Disorders (LEAD), Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhi-Han JiaoDepartment of Anesthesiology, Songjiang Research Institute, Shanghai Key Laboratory of Emotions and Affective Disorders (LEAD), Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Hoiyin CheungDepartment of Anesthesiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xin-Yu ZhaoDepartment of Anesthesiology, Songjiang Research Institute, Shanghai Key Laboratory of Emotions and Affective Disorders (LEAD), Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xin BianDepartment of Anesthesiology, Songjiang Research Institute, Shanghai Key Laboratory of Emotions and Affective Disorders (LEAD), Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Qin JiangDepartment of Anesthesiology, Songjiang Research Institute, Shanghai Key Laboratory of Emotions and Affective Disorders (LEAD), Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ying LiDepartment of Anesthesiology, Songjiang Research Institute, Shanghai Key Laboratory of Emotions and Affective Disorders (LEAD), Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Michael X ZhuDepartment of Integrative Biology and Pharmacology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA.ORCID http://orcid.org/0000-0002-5676-841X
Lu-Yang WangProgram in Neuroscience and Mental Health, SickKids Research Institute, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0002-5399-944X
Yulong LiState Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Beijing, China.ORCID http://orcid.org/0000-0002-9166-9919
Ju HuangDepartment of Anesthesiology, Songjiang Research Institute, Shanghai Key Laboratory of Emotions and Affective Disorders (LEAD), Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID http://orcid.org/0000-0003-4280-0690
Qian LiDepartment of Anesthesiology, Songjiang Research Institute, Shanghai Key Laboratory of Emotions and Affective Disorders (LEAD), Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID http://orcid.org/0000-0003-1300-3377
Wei-Guang LiDepartment of Anatomy and Physiology, Key Laboratory of Anesthesiology (Shanghai Jiao Tong University), Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China. liwg@fudan.edu.cn.ORCID http://orcid.org/0000-0002-3442-7518
Tian-Le XuDepartment of Anesthesiology, Songjiang Research Institute, Shanghai Key Laboratory of Emotions and Affective Disorders (LEAD), Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. xu-happiness@shsmu.edu.cn.ORCID http://orcid.org/0000-0002-1438-0038
Funding
Foundation of Shanghai Municipal Commission of Health and Family Planning (Shanghai Municipal Commission of Health and Family Planning Foundation) 2022XD046Foundation of Shanghai Municipal Commission of Health and Family Planning (Shanghai Municipal Commission of Health and Family Planning Foundation) 2024ZDXK0050Ministry of Science and Technology of the People's Republic of China (Chinese Ministry of Science and Technology) STI2030-Major Projects, 2021ZD0202800National Natural Science Foundation of China (National Science Foundation of China) 32071023, 32371078National Natural Science Foundation of China (National Science Foundation of China) 32200821National Natural Science Foundation of China (National Science Foundation of China) 32300843National Natural Science Foundation of China (National Science Foundation of China) 32430040Science and Technology Commission of Shanghai Municipality (Shanghai Municipal Science and Technology Commission) 22XD1420700Science and Technology Commission of Shanghai Municipality (Shanghai Municipal Science and Technology Commission) 23YF1433900
Abstract
Engrams are formed by activity-dependent recruitment of subsets of excitatory principal neurons, whereas inhibitory neurons mediate memory lability and stability. It remains elusive whether specific types of interneurons are preferentially engaged in determining the fate of memory. Here we show, in male mice undergoing cued fear memory training and extinction, that neuropeptide Y (NPY)-expressing (NPY
Indexed as
CA1 Region, HippocampalInterneuronsMemoryNeuronsNeuropeptide YAnimalsExtinction, PsychologicalFearMaleMiceMice, Inbred C57BLMice, TransgenicNeural InhibitionReceptors, Neuropeptide YNeuropeptide Yneuropeptide Y2 receptorNpy1r protein, mouseReceptors, Neuropeptide Y
Identifiers
PMID
41917464What Socratic holds
Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.