Evidence mapPaperPMID 41917639Full record

ReviewAdvances in experimental medicine and biology2026

The Role of Exercise in Fat Oxidation and Its Impact on Adolescent Metabolism.

Atilla Engin, Ayse Basak Engin

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Review in Advances in experimental medicine and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Atilla EnginFaculty of Medicine, Department of General Surgery, Gazi University, Besevler, Ankara, Turkey.
Ayse Basak EnginFaculty of Pharmacy, Department of Toxicology, Gazi University, Hipodrom, Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adolescent obesity is a major international public health problem. Many studies have shown that exercise training is of great importance in preventing the excessive amount of increase in body fat mass. It has been thought that exercise programs that increase the rate of fatty acid oxidation (FAO) will result in an acceptable reduction in fat mass after a period of time. However, it is still questionable which exercise, and its intensity is most effective for increasing the fat loss. The aim of this review is to discuss exercise intensity-dependent energy consumption and the contribution of lipid oxidation to supply energy demand in the metabolic adaptation of adolescent metabolism to exercise training. A constant sedentary lifestyle leads to insulin resistance and vascular function problems, and an increased rate of carbohydrate oxidation ultimately leads to the accumulation of body fat mass. The exercise program to be implemented in sedentary behavior is decided by monitoring frequency, intensity, time, and type of exercise. Increased adipose tissue perfusion dependent on exercise intensity, results in increased FAO and lipolysis. Surprisingly, lipolysis during high-intensity exercise is less than FAO during low-intensity exercise. A positive correlation has been found between maximum FAO and insulin sensitivity in healthy adolescents.

Indexed as

Adipose TissueEnergy MetabolismExerciseFatty AcidsLipid MetabolismObesityAdolescentCarbohydrate MetabolismHumansInsulin ResistanceLipolysisOxidation-ReductionFatty AcidsAdolescence obesityCarbohydrate oxidationCarnitine metabolismExercise intensitiesFat mass and obesity-associated genesFatty acid oxidationMaximal fat oxidationObese adolescents and fat oxidationPhysical activitySedentary behavior

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.