Evidence map›Paper›PMID 41918667›Full record

ArticleCureus2026

Brainstem Encephalitis Following COVID-19 Vaccination: A Case Report.

Akihito Koseki, Youji Suzuki, Shugo Uchida, Naoki Morishita, Naoki Sakai

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Akihito KosekiNeurology, Yaizu City Hospital, Yaizu, JPN.
Youji SuzukiNeurology, Yaizu City Hospital, Yaizu, JPN.
Shugo UchidaNeurology, Yaizu City Hospital, Yaizu, JPN.
Naoki MorishitaNeurology, Yaizu City Hospital, Yaizu, JPN.
Naoki SakaiNeurology, Yaizu City Hospital, Yaizu, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Encephalitis is an extremely rare neurological adverse event following vaccination against coronavirus disease 2019 (COVID-19). We report a case of brainstem encephalitis following mRNA COVID-19 vaccination. A 30-year-old Japanese female presented with acute diplopia characterized by recurrent, paroxysmal episodes following the second dose of the vaccine, which resolved spontaneously. Brain magnetic resonance imaging revealed inflammatory changes in the brainstem. The patient responded rapidly to steroid therapy and subsequently improved. This case shares key clinical features with another case, including similarities in symptoms, lesion localization, and steroid responsiveness. However, it differs with respect to the timing of symptom onset and the presence of mild residual deficits. This report makes a contribution to the limited literature on this rare post-vaccination condition by documenting its clinical features.

Indexed as

adverse eventbrainstem encephalitiscovid-19covid-19 vaccinesmrna vaccines

Identifiers

PMID41918667
PMCPMC13033411

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.