Evidence map›Paper›PMID 41918906›Full record

ReviewFrontiers in physiology2026

The interaction between sarcoplasmic reticulum and mitochondria: a novel mechanism for cardiac arrhythmia.

Zhongyang Yu, Meng Zhao, Hongyue Xu, Ji Sun, Xiaoxing Jin

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhongyang Yu *State Key Laboratory of Cardiovascular Diseases, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.
Meng Zhao *State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research, Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, China.
Hongyue Xu *State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research, Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, China.
Ji SunDepartment of Cardiology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Xiaoxing JinDepartment of Cardiovascular Medicine, Fifth Affiliated Hospital of Sun Yat-sen University, Zhu Hai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular diseases are a major cause of morbidity and mortality worldwide. Cardiac arrhythmias, especially fatal ventricular arrhythmias, are highly harmful to patients and can even lead to sudden death. While electrical and structural remodeling of myocardial tissue represent the mainstream mechanisms underlying arrhythmogenesis, there is a critical need to explore novel perspectives. This review focuses on the communication between the sarcoplasmic reticulum and mitochondria as an independent mechanistic lens. We detail how this specific interaction governs Ca

Indexed as

a novel mechanismcardiac arrhythmiamitochondriasarcoplasmic reticulumSR-mitochondria interaction

Identifiers

PMID41918906
PMCPMC13033572

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.